Structural thermodynamics by cryo-EM resolves minute energy differences in heterogeneous protein complexes. www.biorxiv.org/content/10.64898/2026.10.07.756995v1 #cryoEM

Structural thermodynamics by cryo-EM resolves minute energy differences in heterogeneous protein complexes. www.biorxiv.org/content/10.64898/2026.10.07.756995v1 #cryoEM
Fusion Peptide Insertion Configuration Determines the Mechanism of Membrane Curvature Induction in Human Parainfluenza Virus Type 3 www.biorxiv.org/content/10.64898/2026.10.07.757304v1 #cryoEM
Defense-associated reverse transcriptases synthesize DNA in a telomerase-like manner www.biorxiv.org/content/10.64898/2026.10.08.757509v1 #cryoEM
Purification-free cryo-EM reveals endogenous assemblies from minute tardigrade samples www.biorxiv.org/content/10.64898/2026.10.08.757488v1 #cryoEM
3D reconstruction of a model phytophagous mite at nano-resolution reveals a peculiar ingestion and digestion system and structural adaptation for a tiny animal pubmed.ncbi.nlm.nih.gov/42847006/ #cryoEM
Establishing the molecular basis for MDA5 mutation-linked autoimmunity pubmed.ncbi.nlm.nih.gov/42847245/ #cryoEM
Effects of high light and elevated temperature on the structure of photosystem II isolated from Arabidopsis thaliana pubmed.ncbi.nlm.nih.gov/42848133/ #cryoEM
Some artistic work from our team highlighting #cryoEM with the Krios Cryo-TEM on the phycobilisome, the light-harvesting machinery in cyanobacteria. PDB 7SC8 was resolved to 2.1 Å.
Explore Krios 5 Cryo-TEM capabilities. ter.li/gzd7lqah
Structural and Mechanistic Insights Into GSDME Pore Formation and Functional Regulation pubmed.ncbi.nlm.nih.gov/42848328/ #cryoEM
Mechanisms of intracellular pH gating and local anesthetic inhibition of the two-pore domain K+ channel TASK-2 pubmed.ncbi.nlm.nih.gov/42848420/ #cryoEM
Receptor-induced activation of MERS-CoV spike revealed by time-course cryo-EM pubmed.ncbi.nlm.nih.gov/42848779/ #cryoEM
Mechanistic insights into chromatin modulation by the "orphan" remodeler ATRX pubmed.ncbi.nlm.nih.gov/42849442/ #cryoEM
Gold Electron Microscopy Grids with Anisotropic Foil Geometry Enable On-Grid Contact Guidance pubmed.ncbi.nlm.nih.gov/42849498/ #cryoEM
Structure-based design and immunogenicity of an H5 hemagglutinin stem nanoparticle vaccine candidate pubmed.ncbi.nlm.nih.gov/42849673/ #cryoEM
Cryo-EM structure of a methanogen nitrogenase–PII protein supercomplex
#methanogens #nitrogen #CryoEM #MicroSky #ArchaeaSky
@nature.com
www.nature.com/articles/s41...
CryoSHIELDs: tunable amphipathic peptide additives for cryo-EM www.biorxiv.org/content/10.64898/2026.10.01.755993v1 #cryoEM
Here you can see the cryoEM structure of DRT2-RT-ncRNA binary complex from Klebsiella pneumoniae (PDB code: 9JL3)
Rendering by Francisco J. Enguita made with #ProteinImager
#SciArt #molecularart #klebsiella #ncRNA #complex #drt2 #immunity #transcription #cryoem
The Dilated Cardiomyopathy E525K Mutation Stabilizes the Cardiac Myosin Interacting-Heads Motif While Activating the Isolated Motor Domain www.biorxiv.org/content/10.64898/2026.10.02.756299v1 #cryoEM
Grateful for funding by @DFF @novo-nordisk.bsky.social @lundbeckfonden.bsky.social
#ProteinDesign #DeNovoDesign #IonChannels #Stroke #CryoEM #Electrophysiology #DrugDiscovery
CryoCodex: learning discrete structural representations for cryo-EM map post-processing www.biorxiv.org/content/10.64898/2026.09.30.755675v1 #cryoEM