@yeastgenome.bsky.social🕳️ #Yeast CCP isn't just an H₂O₂ scavenger, it's a sensor. When H₂O₂ spikes in respiring mitochondria, hole hopping oxidizes H175, releasing the heme to activate catalase A and keep the ETC running efficiently.
Also, oxene≠ox...or does it?
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
@yeastgenome.bsky.social🔬 Single #Yeast cells trapped in alginate microspheres ➡️ every division is traceable. Confocal microscopy + a mathematical formula reconstructs the full replicative history of a founder cell, revealing age of every cell in the microcolony
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
@yeastgenome.bsky.social🔄 A single amino acid change in histone H2A causes transcription chaperone yFACT to pile up at the wrong end of genes. H2A's docking domain is essential for yFACT to release properly after transcription @micropub7n.bsky.social
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
@yeastgenome.bsky.social🥝🍷 Spontaneous fermentation makes complex wines but risks spoilage. High #Yeast inoculum in semi-spontaneous kiwifruit fermentation cuts acetic acid while retaining indigenous microbiota that boost fruity esters and floral terpenoids
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...
@yeastgenome.bsky.social⚗️ Getting proteins out of #Yeast efficiently isn't just a downstream problem. Cultivation pH, growth phase, culture mode & glucose availability all reshape the cell wall, directly affecting how much protein mild disruption can recover
🧬 #YeastResearch 🧪 #SGD 🔬
@yeastgenome.bsky.socialA plug-n-play platform for evolving yeast rDNA identifies variants that improve noncanonical amino acid incorporation across tRNA synthetase/tRNA pairs, establishing ribosome engineering as a route to eukaryotic genetic code expansion
🧬 #YeastResearch 🧪 #SGD 🔬
@yeastgenome.bsky.social⚗️ L-tartaric acid is essential for food and pharmaceuticals but typically extracted from grapes. #Yeast can now make it from scratch via a de novo pathway combining computational enzyme mining, cofactor engineering, & protein design
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...