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@yeastgenome.bsky.socialOct 9, 2026, 12:32 AM

🩺 #Yeast as a disease model: a screen in cardiolipin-deficient yeast identified ebselen as a mitochondrial rescue compound effective across seven fungal models of mitochondrial disease, patient fibroblasts, cardiomyocytes and mice
🧬 #YeastResearch 🧪 #SGD 🔬

www.yeastgenome.org/reference/S1...

@tmlr-pub.bsky.socialOct 8, 2026, 4:31 PM

New #TMLR-Paper-with-Video:

Design Criteria for SGD Preconditioners: Local Conditioning, Noise Floors, and Basin Stability

Mitchell T. Scott, Tianshi Xu, Ziyuan Tang et al.

https://tmlr.infinite-conf.org/paper_pages/vo8FOBt6f6

#sgd #minimizer #gradient

Design Criteria for SGD Preconditioners: Local Conditioning, Noise Floors, and Basin Stability
@terumbudivers.comOct 8, 2026, 3:58 PM

a 2 floors hjome for turtles
#gili #giliislands #lombok #diving #scuba #singapore #trawangan #diveandstay #giliair #sgd #ocean #sealife #marinelife #turtle #greenturtle #turtles

a sea turtle on a big sponge and a second one below on the floor, scuba diving in lombok gili indonesia
@yeastgenome.bsky.socialOct 7, 2026, 11:32 PM

📊 Different methods for profiling #Yeast cell walls capture different things. Scatter-based flow cytometry tracks mannan abundance; lectin fluorescence reflects surface composition. Approaches are complementary rather than interchangeable
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

@yeastgenome.bsky.socialOct 7, 2026, 4:23 PM

Catching up on a #yeast gene? Start with the Literature section on #SGD gene pages. New: a chart of curated papers by year, plus the latest publications. The full curated set of papers, organized by relevance, is only one click away. #UIupdate www.yeastgenome.org/blog/new-lit...

Bar graph of curated ATG8 publications by year on its SGD gene page, followed by a list of the most recent papers.
@faszi-fankurve.bsky.socialOct 7, 2026, 9:57 AM

Aktiver Support & Pyro auf beiden Seiten bei FK Teplice vs. SG Dynamo Dresden. Mehr dazu hier im Artikel ➡️
www.faszination-fankurve.de/news/128443/aktiver-support-pyro-auf-beiden-seiten-bei-fk-teplice-vs-sg-dynamo-dresden 📸: @UiSF_UiSF #ultras #sgd #dynamodresden #teplice #pyro

@yeastgenome.bsky.socialOct 6, 2026, 8:49 PM

🖖 What drives replicative aging in #Yeast? An @oregonstate.edu 🦫 screen found 132 variant genes & 60 differentially expressed genes with little overlap, suggesting longevity is governed by many genes through diverse mechanisms

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

@diesachsen.bsky.socialOct 6, 2026, 8:19 AM

Dynamo Dresden bangt um Thomas Keller: Nach seiner Gehirnerschütterung lässt Trainer Thomas Stamm kein Risiko zu. Ein Comeback in Osnabrück ist ungewiss. #Dynamo #DynamoDresden #ThomasKeller #2.Bundesliga #DynamoDresdennews #DynamoDresdenaktuell #SGD #sgd1953 #VFLSGD #1953update
www.diesachsen.de

@terumbudivers.comOct 6, 2026, 2:22 AM

A big bed for a small turtle
#gili #giliislands #lombok #diving #scuba #singapore #trawangan #diveandstay #giliair #sgd #ocean #sealife #marinelife #turtle #greenturtle #turtles

a sea turtle is on a huge pink red sponge, scuba diving lombok gili indonesia
@yeastgenome.bsky.socialOct 5, 2026, 10:54 PM

✂️ A nonessential #Yeast spliceosome factor w/conserved domain touching the catalytic core turns out to matter more than expected: Cwc15 stabilizes active site & facilitates structural transitions, implications for splice site proofreading
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

@yeastgenome.bsky.socialOct 5, 2026, 6:03 PM

The first integrated #eukaryotic #genome #database has now been running for 30+ years. 🧬 A new history of #SGD traces how a #Stanford #yeast database became a global hub for #genetics, functional #genomics & #humanDisease research. 📄 bit.ly/SGD30FEMSYeast #bioinformatics

Thirty years of sustained growth in SGD literature coverage and biological annotation. The figure shows two measures of SGD’s expansion from 1996 to 2025. The black line represents cumulative papers incorporated into the database, reflecting the pace at which published yeast research has been integrated. Stacked bars show cumulative annotations across major annotation types, ordered from bottom to top by year of first curation: locus summaries (orange, since 1999), GO annotations (green, since 2002), phenotype annotations (blue, since 2006), allele annotations (red, since 2006), regulation annotations (purple, since 2016), PTM annotations (cyan, since 2017), disease annotations (pink, since 2018), and functional complementation (brown, since 2021). The progressive accumulation of annotation types, visible as new colored segments appearing over time, illustrates SGD’s transformation from a genome sequence database into a comprehensive biological knowledge resource. Three vertical dashed lines mark key milestones in SGD’s history: (1) database launch and first annotations, (2) adoption of GO, and (3) expansion into disease-focused curation. By 2025, SGD contained ~100 000 papers and over 500 000 annotations spanning diverse data types.
@yeastgenome.bsky.socialOct 3, 2026, 3:58 AM

🧘 #Yeast RPL22 pre-mRNA acts as its own regulator. The intron toggles between 2 competing structures: one blocks splicing, one permits it. Rising Rpl22 levels shift the balance toward inhibition, creating a protein-responsive RNA switch

🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

@yeastgenome.bsky.socialOct 3, 2026, 12:44 AM

♻️ #Yeast Acs2 generates acetyl-CoA locally at chromatin, while its mammalian ortholog ACSS2 also recaptures acetate from histone deacetylation at promoters. This acetate recycling loop couples metabolism ↔️ chromatin state across species
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

@diesachsen.bsky.socialOct 2, 2026, 11:00 AM

Mika Baur schreibt Geschichte: Der Ex-Dynamo-Spieler ist beim 2:0 gegen Serbien der 1000. Nationalspieler des DFB. #Dynamo #Dresden #MikaBaur #DynamoDresden #DFB #Nationalmannschaft #SGD #sgd1953 #Dynamonews #DynamoDresdenaktuell #DynamoDresdennews #1953update
www.diesachsen.de

@yeastgenome.bsky.socialSep 30, 2026, 5:01 PM

🏋️ Not all #Yeast strains handle acetic acid equally. Respiratory capacity and carbon flux determine survival under acid stress, and two S. cerevisiae strains show strikingly different responses with implications for strain engineering

🧬 #YeastResearch 🧪 #SGD 🔬

www.yeastgenome.org/reference/S1...

@yeastgenome.bsky.socialSep 29, 2026, 9:33 PM

🧲 How does #Yeast CAF-1 find the replication fork to deposit histones? Via PCNA, using not 1 but 2 PIP motifs. The newly found PIP1β makes atypical extended contacts w/second PCNA subunit; disrupting both motifs abolishes CAF-1 function
🧬 #YeastResearch 🧪 #SGD 🔬

www.yeastgenome.org/reference/S1...

@yeastgenome.bsky.socialSep 28, 2026, 8:55 PM

🗑️ #Yeast nuclear ubiquitin ligase Uls2 has surprising side job: tagging cytosolic proteins for degradation. Orphaned/ oxidatively damaged proteins aggregate in nucleus & become SUMO-dependent substrate ➡️ = compartment-spanning QC pathway
🧬 #YeastResearch 🧪 #SGD 🔬
www.yeastgenome.org/reference/S1...

@terumbudivers.comSep 28, 2026, 8:44 PM

Let's go to breathe
#gili #giliislands #lombok #diving #scuba #singapore #trawangan #diveandstay #giliair #sgd #ocean #sealife #marinelife #turtle #greenturtle #turtles

a turtle is swimming up, diving lombok gili indonesia
@terumbudivers.comSep 28, 2026, 3:52 PM

Turtle is sleeping on a sandy bottom
#gili #giliislands #lombok #diving #scuba #singapore #trawangan #diveandstay #giliair #sgd #ocean #sealife #marinelife #turtle #greenturtle #turtles

a sea turtle from above rests on the sand, diving lombok gili indonesia
@tmlr-pub.bsky.socialSep 28, 2026, 12:21 AM

Gradient Heterogeneity Complements Hessian Heterogeneity in Transformer Optimization

Akiyoshi Tomihari, Issei Sato

Action editor: Konstantin Mishchenko

https://openreview.net/forum?id=wZJcQb5m1e

#transformer #optimizers #sgd

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