Restoration of aged liver regeneration by youthful systemic factors via LTβ-driven hepatocyte reprogramming

#LiverResearch #LiverSky #Hepatology
https://doi.org/https://www.sciencedirect.com/science/article/pii/S016882782602893X?dgcid=rss_sd_all

AASLD, #AST, and #NASPGHAN have developed evidence-based guidelines to support clinicians across the #pediatriclivertransplant journey.

📗 Candidate evaluation in #HEPATOLOGY: https://bit.ly/4d2DMJ8
📙 Posttransplant management in #LiverTransplantation: https://bit.ly/4AATVjd

You don't want to miss the first virtual event for the Summer Liver Academy Meeting (SLAM) Community. Join us on October 15 for a fantastic talk from Dr. Zhenghui Jiang https://bit.ly/3V6iIet

#SLAM #LiverResearch #MASLD #ALD #Hepatology @harvardmed.bsky.social

Could CRRT help before kidney failure develops in acute liver failure?

Early CRRT improved ammonia clearance and early outcomes, but definitive survival benefit remains unproven.

#AcuteLiverFailure #Hepatology #CRRT #MedSky

🔥 HOT TOPIC: A new path toward a functional cure for chronic #hepatitis B is taking shape.

This randomized trial explores combining nucleos(t)ide withdrawal with pegylated interferon to help inform future treatment strategies.

Read the article in #HEPATOLOGY: https://bit.ly/3VLgxgH

Targeting RPL4 in combination with PD-L1 blockade achieves near-complete resolution of liver fibrosis.

#LiverFibrosis #LiverSky #Hepatology
https://doi.org/10.1016/j.xcrm.2026.103056

Integrated single-cell multiomics reveals neutrophil-driven immune-metabolic reprogramming of Kupffer cells via thrombospondin-1/CD36 after surgical stress

#LiverImmunology #LiverSky #Hepatology
https://doi.org/https://insight.jci.org/articles/view/203495

Vitamin D receptor (VDR) signaling in macrophages is essential for limiting fibrosis, acting through a previously unrecognized metabolic epigenetic circuit.

#LiverImmunology #LiverSky #Hepatology
https://doi.org/10.64898/2026.09.15.751751

🧠 What happens when the liver and brain intersect?

Prof Dr Valérie McLin gives a glimpse into her latest #ESPGHANPodcast, exploring the complex liver–brain connection in children.

🎧 Curious to hear more? Listen to the full episode on your preferred platform: t.co/zHK80rkrNt

#ESPGHAN #Hepatology

Combination therapy shows promise in #schistosomiasis care.

YCHD and PZQ reduce #granulomatous inflammation and #fibrosis by inhibiting apoptosis and ER stress, offering therapeutic promise. #medsky

To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology

New mechanistic insight into estrogen induced #cholestasis.
Elevated miR 128 3p downregulates #PDZK1, promoting MRP2 internalization and cholestatic injury. Suppressing miR 128 3p restores PDZK1 and bile transport. #medsky #Hepatology
#AMM #OpenAccess: doi.org/10.15212/AMM...

PBC assessment is moving beyond ALP alone.

The 2026 EASL–AASLD consensus keeps ALP and bilirubin central, while placing greater emphasis on fibrosis trajectory, symptoms, and multidimensional disease control.

gastroagi.com/daily-brief

#PBC #Hepatology #Gastroenterology #AASLD #MedSky

This study summarizes the role of #TranscriptionFactors in #ALD pathology—from lipid metabolism to ER stress—and highlights promising targeted therapies for ALD treatment. #medsky

Read more: doi.org/10.1007/s115...

#currentmedicalscience #Hepatology #Epigenetics

Restoring liver glutamine suppresses inflammation and limits liver injury. These findings identify T cell glutamine metabolism as a key metabolic checkpoint and promising therapeutic target in MASLD.

#MASLD #LiverResearch #LiverSky #Hepatology
https://doi.org/10.1016/j.cmet.2026.08.018

Calling all liver lovers! We are excited to announce the first virtual event for the Summer Liver Academy Meeting (SLAM) Community. Join us on October 15 for a fantastic talk from Dr. Zhenghui Jiang https://bit.ly/3V6iIet

#SLAM #LiverResearch #MASLD #ALD #Hepatology

Can a natural compound protect the #Liver from alcohol induced iron overload?

This study reveals that #quercetin sustains ferritinophagic flux & lysosomal function via #FOXO1 TFEB NCOA4 signaling. #medsky
To read: doi.org/10.1007/s115...

#currentmedicalscience #Hepatology

#LiverCancer Special Issue Now Online in #HEPATOLOGY!

▶️ Watch Associate Editors Jordi Bruix, MD, PhD, & Sumera Ilyas, MD, introduce the issue and highlight what readers can expect from this curated collection.

➡️Read️ https://bit.ly/4hxccGq

www.youtube.com/watch?v=4Hg7zXAYlpc

📢 Join the Early Career Editorial Board of #LiversMdpi

🎓 Livers is recruiting early-career researchers worldwide to join its ECEB and contribute their academic insights and professional expertise.

🔗 More Information: brnw.ch/21x48Mr

#Hepatology #AcademicRecruitment #EarlyCareerResearcher

Zonated cholesterol sensing by SIRT2 drives MASLD-HCC

#MASLD #LiverResearch #LiverSky #Hepatology
https://doi.org/10.1016/j.cmet.2026.08.015