Fantastic to not only see the final version of the paper published but also have it featured on the cover of the October issue of @insight.jci.org 🎉🎉🎉 #endothelialcells #liver #fibrosis
@neildufton.bsky.social
@neildufton.bsky.socialFantastic to not only see the final version of the paper published but also have it featured on the cover of the October issue of @insight.jci.org 🎉🎉🎉 #endothelialcells #liver #fibrosis
@liversmdpi.bsky.social📢 New Review in #LiversMDPI
🧬 Ichimura-Shimizu et al. propose a mechanism-oriented framework for MASH model selection.
đź©ş Covers iHFC diet and TSOD/TSNO mouse models in a complementary landscape.
đź“– Read More: www.mdpi.com/2673-4389/6/...
@genesndiseases.bsky.socialCould reprogramming #Tregs limit #RadiationInducedLungInjury?
This study identifies the METTL3/miR-223-3p/Lif axis as a regulator of Treg differentiation and #fibrosis, revealing a potential therapeutic target.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
@tenuretracker.bsky.socialKarolinska Institute (@ki.se) is hiring:
Postdoctoral Researcher in Human Translational Fibrosis and Metabolic Disease
@aegeanconf.bsky.social🎓 Congratulations to our 13 Trainee Travel Award recipients at the 5th International Conference on Tissue Repair, Regeneration & Fibrosis! 🧬
Proud to support the next generation of scientists! đź‘Ź
@embomolmed.org#ProstaglandinE2 -mediated aging microenvironment fuels pathogenic #fibrosis in #CesareanSection scar defect
By Y. Yin, Z. Li, X. Wang & colleagues Tongji University & Shanghai Jiao Tong University School of Medicine
@fcp-sfpt.bsky.social@genesndiseases.bsky.socialHow does epigenetic dysregulation drive kidney disease?
#DNMT1 regulates renal inflammation, cell proliferation, apoptosis, #fibrosis and metabolic stress, making it a potential target for #KidneyDisease therapy.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
@dctomaz.bsky.social🧬 A 77-liver single-cell atlas identifies OLR1+ macrophages associated with fibrosis. Targeting OLR1 reduced fibrogenic activity in human cell models—a candidate target, not a validated treatment. doi.org/10.1038/s415... #Immunology #Fibrosis
@aegeanconf.bsky.social🇬🇷 Welcome to Crete!
We’re excited to welcome participants tonight for the 5th International Conference on Tissue Repair, Regeneration & Fibrosis in Sissi, Crete!
We look forward to an outstanding week of science, discussion & collaboration. 🧬
#TissueRepair #Regeneration #Fibrosis #AegeanConferences
@labmed2025.bsky.socialWhat fuels kidney fibrosis in IgG4-related disease?
This LMD review explores how metabolic reprogramming and immune dysregulation intertwine—and highlights potential targets for future therapies.
@northwell-journals.bsky.socialMolecular Medicine - Journal
Article in Press: Urinary collagen type I degradation products as common fibrosis biomarkers in chronic diseases | #MolecularMedicine #Fibrosis #Biomarkers #CKD link.springer.com/article/10.1...
@liversmdpi.bsky.social📢 New Review in #LiversMDPI
🧬 Kaur et al. review PPAR agonists across PBC and other liver diseases.
đź©ş The review covers molecular pharmacology and clinical and preclinical evidence.
đź“– Read More: www.mdpi.com/2673-4389/6/...
@currentmedscience.bsky.socialCombination therapy shows promise in #schistosomiasis care.
YCHD and PZQ reduce #granulomatous inflammation and #fibrosis by inhibiting apoptosis and ER stress, offering therapeutic promise. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
@liversmdpi.bsky.social📢 Call for Reading in #LiversMDPI
🔬 Villanueva Raisman et al. quantified 108 proteins in 2 µL of plasma.
🧬 Potential biomarkers for stratifying liver fibrosis were identified.
đź“– Read More: brnw.ch/21x5oWo
@sigtrans-sttt.bsky.socialTargeting ROCK2 may offer a therapeutic approach for chronic graft-versus-host disease (#cGVHD). This phase Ib study finds encouraging responses and a manageable safety profile with TDI01, a highly selective ROCK2 inhibitor.
#STTT #OpenAccess: doi.org/10.1038/s413...
#Fibrosis #TCellImmunity
@dctomaz.bsky.social🧬 Tissue repair is essential—but what happens when it doesn’t switch off? An interesting perspective on how persistent inflammation and repair programmes contribute to fibrosis, and where we might intervene.
#Immunology #Fibrosis
@gmj-georgia.bsky.socialBreaking: Semaglutide (Wegovy) becomes the first GLP-1 receptor agonist approved to treat metabolic dysfunction-associated steatohepatitis (MASH) with moderate-to-a… #Drugapproval #Fibrosis #GLP1agonists #Hepatology #Liverdisease #Drugapproval #Fibrosis #GLP1agonists #Hepatology #Liverdisease …
@jem.orgZhang et al. identify RalA-dependent signaling as a regulator of age-related #skeletalmuscle dysfunction. The novel compound UA-30 inhibits RalA activity, reduces muscle #fibrosis, improves mitochondrial function & mobility, & extends health span & survival in mice. rupress.org/jem/article/...
@sigtrans-sttt.bsky.socialBCL9 drives the MerTK–ERK–SPP1 macrophage M2 program in #PulmonaryFibrosis, while its inhibition reprograms macrophage–fibroblast crosstalk toward fibroblast #Lipogenesis, supports AT2 cell expansion and attenuates #Fibrosis.
