ChIP-CryoEM is used to resolve CENP-A #nucleosomes isolated from human cells, which are shown to be octameric and to retain hallmark CENP-A features, defining the structural organization of centromere-specifying #chromatin.
nature.com/articles/s42003-026-10946-x

Epigenetics Update - Euchromatin forms condensed domains with short active regions on the surface www.nature.com/articles/s41...

Joseph M. Paggi and binzmit.bsky.social (mit.edu) in Nature Genetics

#Epigenetics #Euchromatin #Chromatin
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Epigenetics Update - Enhancer Tuning by Sequence-Specific Repressors www.biorxiv.org/content/10.6...

lichino.bsky.social and Joanna Wysocka (stanfordmedicine.bsky.social) in BioRxiv

#Epigenetics #Enhancers #Chromatin #DAFseq
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Gain deeper insights into gene regulation; epigenometech.com

6/ ==> First structural view of transcription through chromatin in archaea. Thanks to all co-authors! ☺️
#archaeaSky #chromatin #transcription

Epigenetics Update - Atlas of cell types and regulatory elements underlying human facial diversity www.nature.com/articles/s41...

alekerickson.bsky.social, Yaakov Gershtein, and Rozalina Galimullina in Nat Genet

#Epigenetics #FacialDiversity #Chromatin
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epigenometech.com

👉Evolution, application and clinical significance of profiling chromatin interactions at a genome-wide scale
www.sciengine.com/ABBS/doi/10....
#chromatin
#next-generation sequencing
#transcription factor
#super enhancer
#single-cell multi-omics
#long-read sequencing

👉Evolution, application and clinical significance of profiling chromatin interactions at a genome-wide scale

www.sciengine.com/ABBS/doi/10....

#chromatin
#next-generation sequencing
#transcription factor
#super enhancer
#single-cell multi-omics
#long-read sequencing

Epigenetics Update - Divergent SAGA complexes shape the Toxoplasma transcriptome for lytic cycle progression and host interaction www.nature.com/articles/s41...

hakimi.bsky.social (University Grenoble Alpes) in Nat Commun

#Epigenetics #Chromatin #Toxoplasma #SAGA
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epigenometech.com

Epigenetics Update - Switching of transcriptional control from interferon regulatory factor 2 to interferon regulatory factor 1 drives innate immune cell activation www.cell.com/cell/fulltex...

#Epigenetics #Immunity #Chromatin #Interferon
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Empower your research at epigenometech.com

Epigenetics Update - HOMEODOMAIN-LIKE shapes chromatin architecture and rewires leaf epidermal patterns www.nature.com/articles/s41...

Ansar Ali and Chin-Min Kimmy Ho (Academia Sinica) in Nature Communications

#Epigenetics #Chromatin #Plants #Leaf
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University of Oslo is hiring:
PhD Fellowship in Spatial Genome Organization and Gene Regulation

#phd #biology #chromatin

Epigenetics Perspective - Promotion of long-term health in early life u.epigenome.us/k1iVzU4W

Martin Stocker (uniluzern.bsky.social) in PNAS

#Epigenetics #Chromatin #Aging #Perspective
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Epigenetics Update - Transgenerational inheritance of altered H3K27me3 in wild-type Caenorhabditis elegans u.epigenome.us/KFiE6Ejh

Florian A Steiner (biology-unige.bsky.social) in embojournal.org

#Epigenetics #H3K27me3 #Chromatin
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Gain hi-res at epigenometech.com

Epigenetics Update - Epigenetic training licenses naïve CD8+ T cell metabolic fitness and function u.epigenome.us/QNga66gq

Guohong Li and Mingzhao Zhu (CAS) in Science Advances

#Epigenetics #Immunity #Chromatin
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Perfect for cancer, immunology, and aging research; epigenometech.com

Epigenetics Update - Multiomics profiling identifies molecular and cellular signatures of regular exercise in human peripheral blood u.epigenome.us/SIvyBrCi

#Epigenetics #Multiomics #Exercise #Chromatin #Blood
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Epigenetics Update - m6A mRNA methylation regulates pancreatic α-cell plasticity u.epigenome.us/KDgUFM6l

dariofdejesus.bsky.social and Rohit N. Kulkarni (harvardmed.bsky.social) in natmetabolism.nature.com

#Epigenetics #Chromatin #Diabetes
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Epigenetics Update - Myeloid reprogramming generates myeloid-derived activating cells to potentiate radiotherapy and suppress metastasis u.epigenome.us/vsqIsDS3

Hua Laura Liang, Chuan He, & Ralph R. Weichselbaum in Cancer Cell

#Epigenetics #Chromatin #Cancer #MDACs #TET2
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epigenometech.com

Tomorrow! The Physical Genomics Trainee Program Research Showcase featuring talks by PhD students Evelynn Chen and Eric Tong, live on Zoom. Join us!

Registration is free at tinyurl.com/pr5nbkf3

#genomics #northwestern #cpge #biophysics #research #chromatin #biology #womenshealth #transcription

Epigenetics Update - Deletion of a distal IRF4 element prevents inflammation-induced reprogramming of human regulatory T cell fate u.epigenome.us/2JRq9uPW

Patrick Ho and Qizhi Tang (ucsanfrancisco.bsky.social) in natimmunol.nature.com

#Epigenetics #Inflammation #Chromatin
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epigenometech.com

Epigenetics Update - HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling u.epigenome.us/DkINkLJD

Yu Zhang, Yichuan Xiao, & Xianling Cong in Nat Commun

#Epigenetics #Chromatin #Progeria #Aging
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