@infdiseasesnow.bsky.social5➡️Une communication brève évaluant la prévalence de l'infection par le VHE au moment de l'accouchement chez des femmes africaines infectées ou non par le VIH.
www.sciencedirect.com/science/arti...
#IDSky #IDSkyFr #HepatitisEVirus #Infection #Seroprevalence #Antibodies #PregnantWomen
@antibodytx.bsky.socialAntibody Therapeutics (IF=4.8, Oxford University Press) ⚡ Review Highlight -CAR NK cell therapy for solid tumors: potential and challenges
doi.org/10.1093/abt/...
#mab #mabs #antibody #antibodies #antibodydiscovery #antibodytherapeutics #biologics #naturalkillercells #CAR #CARNK
@plosbiology.orgBroadly neutralizing #flu #antibodies able to recognize both influenza A and B viruses are exceptionally rare. This study shows that mutations that promote binding to one flu virus can weaken recognition of others, constraining antibody cross-reactive breadth.
🧪 #ImmuneSky
plos.io/4z8mzGV
![Structural analysis of the differential effects on binding affinity.
(A) The Cαs of VH S24, VH S52, VH F54, and VH I73 in CR9114 are shown as spheres (PDB 4FQI) [15]. CR9114 and HA are in blue and white, respectively. The local chemical environment for (B) VH S24, (C) VH S52 and VH F54, and (D) VH I73 are shown. Black dashed lines represent H-bonds. (E) The structure of HA-bound CR9114 with VH W73 is modeled. Red circle indicates steric clash.](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreifuwvw5kmmb2zxjbcehei52sfn5rrg45wel6we7lajfjvhzjso5ye@jpeg)
@plosbiology.orgBroadly neutralizing #flu #antibodies able to recognize both influenza A and B viruses are exceptionally rare. This study shows that mutations that promote binding to one flu virus can weaken recognition of others, constraining antibody cross-reactive breadth.
🧪 #ImmuneSky
plos.io/4z8mzGV
![Structural analysis of the differential effects on binding affinity.
(A) The Cαs of VH S24, VH S52, VH F54, and VH I73 in CR9114 are shown as spheres (PDB 4FQI) [15]. CR9114 and HA are in blue and white, respectively. The local chemical environment for (B) VH S24, (C) VH S52 and VH F54, and (D) VH I73 are shown. Black dashed lines represent H-bonds. (E) The structure of HA-bound CR9114 with VH W73 is modeled. Red circle indicates steric clash.](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreih4hmbh2bbu62qnbawqwjsdvj662j5amaimo5d4inm3qca6adzlfm@jpeg)
@biotium.bsky.socialRead our New Highlighted Citation featuring a simpler and more cost-effective approach to isolating EVs from raw milk with our ExoBrite™ True EV Membrane Stain!
#milkresearch #biotechniques #antibodies #scienceread #evisolation #flowcytometry #cowmilk #labhelp
@microbesinfo.bsky.social🦟🧬 Researchers identified a vulnerable site on #Plasmodium Vivax that #antibodies can target to block #liver #infection before dormant #malaria #parasites become established.
@lji.orgYour B cells wait, watch, and LEARN. These cells go on an amazing journey to give you the molecular weapons to fight infection!
Go inside the fascinating world of #antibodies with new LJI Research Assistant Professor Parham Ramezani-Rad:
@plosbiology.orgR1-32-like public #antibodies drive #SARSCoV2 #virus to acquire #SpikeProtein mutations that promote #immune escape. This study characterises 4 such antibodies, showing that they acquire tolerance to SARS-CoV-2 antigenic drift via somatic hypermutation @plosbiology.org 🧪 buff.ly/iy4qUOe
@plosbiology.orgR1-32-like public #antibodies drive #SARSCoV2 #virus to acquire #SpikeProtein mutations that promote #immune escape. This study characterises four such antibodies, showing that they acquire tolerance to SARS-CoV-2 antigenic drift via somatic hypermutation @plosbiology.org 🧪 buff.ly/iy4qUOe
@plosbiology.orgR1-32-like public #antibodies drive #SARSCoV2 #virus to acquire #SpikeProtein mutations that promote #immune escape. This study characterises four such antibodies, showing that they acquire tolerance to SARS-CoV-2 antigenic drift via somatic hypermutation @plosbiology.org 🧪 plos.io/3TcJrFA
@microbesinfo.bsky.social🐔🦟 #Delaware uses sentinel #chickens as an early-warning system for #WestNileVirus and #EEE because the #birds develop detectable #antibodies without spreading the #viruses.
#WNV #PublicHealth #Mosquitoes #PublicHealth #Microsky via @theguardian.com
@antibodytx.bsky.socialAntibody Therapeutics (IF=4.8, Oxford University Press) ⚡ Research Highlight -Preclinical development of mecbotamab vedotin (BA3011), a novel, AXL-specific conditional active biologic antibody–drug conjugate.
doi.org/10.1093/abt/...
#mabs #antibody #antibodies #antibodydiscovery
@newsen.bsky.socialJust - Evotec Biologics Launches Phase 1 Trials for Antibodies Against Orthopoxvirus #United_States #Redmond #Antibodies #Just_-_Evotec #orthopoxvirus