@plosbiology.orgPoorly validated #antibodies generate misleading results and waste research resources. @johanduchene.bsky.social explores two new @PLOSBiology.org studies quantifying these costs and identifying solutions.
🧪
Article 1 plos.io/3Ui0czP
Article 2 plos.io/4s1Ccxl
Primer plos.io/4hQh7kI
@newsramp.comCreative Biolabs launches a three-part antibody engineering framework targeting immunogenicity, efficacy, and manufacturability to help researchers accelerate preclinical development pipelines with greater confidence. #Antibodies #Biopharmaceuticals
@plosbiology.orgPoorly validated #antibodies misdirect research, wasting an estimated billion dollars and millions of biological samples each year. In this multi-stakeholder Delphi consensus study, experts agree on priority practical fixes, and who should deliver them, by 2030.
🧪 #AcademicSky
plos.io/3Ui0czP
@plosbiology.orgPoorly validated #antibodies generate misleading results and waste research resources. @johanduchene.bsky.social explores two new @PLOSBiology.org studies quantifying these costs and identifying solutions.
🧪
Article 1 plos.io/3Ui0czP
Article 2 plos.io/4s1Ccxl
Primer plos.io/4hQh7kI
@plosbiology.orgPoorly validated #antibodies misdirect research, wasting an estimated billion dollars and millions of biological samples each year. In this multi-stakeholder Delphi consensus study, experts agree on priority practical fixes, and who should deliver them, by 2030.
🧪 #AcademicSky
plos.io/3Ui0czP
@narrowit.bsky.socialDanaher Plans AI-Powered Lab to Speed Antibody Tool Development Danaher plans an autonomous laboratory linking AI, robotics and equipment from...
https://www.narrowit.com/news/danaher-plans-ai-powered-autonomous-lab-2026-10-07
#Danaher #ArtificialIntelligence #LaboratoryAutomation #Antibodies
@hellobio.bsky.socialChoosing the right antibody can make a big difference to the reliability of your results, and in this new article we share 6 key things to look for in antibody validation evidence 🙌
Read here: https://ow.ly/Eszq50ZVige
#antibody #antibodies #reproducibility #lifescience #validation #lifescience
@vaccinologist.bsky.socialResearchers at the University of South Florida @usf.edu identified a vulnerable site that #antibodies can target to block liver-cell invasion - preventing #infection before hypnozoites are established. Important advance vs. one of #malaria’s most difficult parasites. lnkd.in/p/exmyCQ8G
@retropz.bsky.socialNew #ResearchIntegrity blog from @cancerresearchuk.org on validation of #antibodies:
"If as a focused cancer research community we can embed antibody validation practices, we can protect the integrity of our research"
Rebecca Harris, Therapeutic Innovation team, @crhorizons.bsky.social
@diseaseatlas.bsky.socialHalf the modality question is answered by where the target sits: inside the cell, small molecule; secreted, antibody. Disease Atlas by Euretos scores it from the biology. IL-13 is a secreted cytokine: small molecule not tractable, antibody reads high, two approved. #Antibodies
@akulmehta.bsky.socialIn this study we saw something unexpected. Normally antibodies against blood groups are stable for people, but in some people with SARS-CoV-2 infections we saw changes in their antibody profiles. Please check out our latest work.
#COVID19 #Immunology #BloodGroups #Antibodies #Glycobiology #Glycotime
@thencfg.bsky.socialOur new study reveals SARS-CoV-2 infection causes unpredictable fluctuations in anti-ABO(H) blood group antibodies.
Read the paper at: pubs.acs.org/acbcct/artic...
#COVID19 #Immunology #BloodGroups #Antibodies #Glycobiology #Transplantation #Glycotime
@artificialscience.bsky.socialAI can now draft antibodies on screen. Reported hit rates run from 2% to 38%, but evidence is uneven. See the data: artificialscience.org/2026/10/ai-c...
@plosbiology.orgBroadly neutralizing #flu #antibodies able to recognize both influenza A and B viruses are exceptionally rare. This study shows that mutations that promote binding to one flu virus can weaken recognition of others, constraining antibody cross-reactive breadth.
🧪 #ImmuneSky
plos.io/4z8mzGV
![Structural analysis of the differential effects on binding affinity.
(A) The Cαs of VH S24, VH S52, VH F54, and VH I73 in CR9114 are shown as spheres (PDB 4FQI) [15]. CR9114 and HA are in blue and white, respectively. The local chemical environment for (B) VH S24, (C) VH S52 and VH F54, and (D) VH I73 are shown. Black dashed lines represent H-bonds. (E) The structure of HA-bound CR9114 with VH W73 is modeled. Red circle indicates steric clash.](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreifuwvw5kmmb2zxjbcehei52sfn5rrg45wel6we7lajfjvhzjso5ye@jpeg)
@vanderbiltvicb.bsky.socialVICB member, Dr. James Crowe, and his team have developed potent human monoclonal #antibodies against #measles that have now been licensed by Saravir Biopharma for further development and #clinical testing.
@infdiseasesnow.bsky.social5➡️Une communication brève évaluant la prévalence de l'infection par le VHE au moment de l'accouchement chez des femmes africaines infectées ou non par le VIH.
www.sciencedirect.com/science/arti...
#IDSky #IDSkyFr #HepatitisEVirus #Infection #Seroprevalence #Antibodies #PregnantWomen
@antibodytx.bsky.socialAntibody Therapeutics (IF=4.8, Oxford University Press) ⚡ Review Highlight -CAR NK cell therapy for solid tumors: potential and challenges
doi.org/10.1093/abt/...
#mab #mabs #antibody #antibodies #antibodydiscovery #antibodytherapeutics #biologics #naturalkillercells #CAR #CARNK
@plosbiology.orgBroadly neutralizing #flu #antibodies able to recognize both influenza A and B viruses are exceptionally rare. This study shows that mutations that promote binding to one flu virus can weaken recognition of others, constraining antibody cross-reactive breadth.
🧪 #ImmuneSky
plos.io/4z8mzGV
@plosbiology.orgBroadly neutralizing #flu #antibodies able to recognize both influenza A and B viruses are exceptionally rare. This study shows that mutations that promote binding to one flu virus can weaken recognition of others, constraining antibody cross-reactive breadth.
🧪 #ImmuneSky
plos.io/4z8mzGV
![Structural analysis of the differential effects on binding affinity.
(A) The Cαs of VH S24, VH S52, VH F54, and VH I73 in CR9114 are shown as spheres (PDB 4FQI) [15]. CR9114 and HA are in blue and white, respectively. The local chemical environment for (B) VH S24, (C) VH S52 and VH F54, and (D) VH I73 are shown. Black dashed lines represent H-bonds. (E) The structure of HA-bound CR9114 with VH W73 is modeled. Red circle indicates steric clash.](https://cdn.bsky.app/img/feed_fullsize/plain/did:plc:5522ztebtekoor5efelihqhb/bafkreih4hmbh2bbu62qnbawqwjsdvj662j5amaimo5d4inm3qca6adzlfm@jpeg)
@biotium.bsky.socialRead our New Highlighted Citation featuring a simpler and more cost-effective approach to isolating EVs from raw milk with our ExoBrite™ True EV Membrane Stain!
#milkresearch #biotechniques #antibodies #scienceread #evisolation #flowcytometry #cowmilk #labhelp