@paulschanda.bsky.social
Passionate for integrated structural biology, including NMR and many more. Particularly interested in protein dynamics, and therefore chaperones, enzymes and mitochondrial protein import. Fortunate to lead a great research team at IST Austria.
@iomichiamofede.bsky.socialReposted by @paulschanda.bsky.social🧲 #NMR is for small proteins... without the right tools.
Our new paper is out now in @jacs.acspublications.org
A shared effort with Rajkumar Singh, Anna Kapitonova, Virgil Aitenbichler, @giorgia-toscano.bsky.social, Barbara Perrone and @paulschanda.bsky.social
Paper: doi.org/10.1021/jacs...
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@paulschanda.bsky.social📢 Happy to share our latest publication in @jacs.acspublications.org led by Fede Napoli, showing how different #NMR approaches (solution, solid) provide atomic-level insights into a large #enzyme. Advanced methods, elegantly combined. Congrats @iomichiamofede.bsky.social
pubs.acs.org/doi/10.1021/...
@istaresearch.bsky.socialReposted by @paulschanda.bsky.socialWith projects on AI, astrophysics, bacterial immune systems, quantum matter, and optics, five ISTA researchers have secured €9.2 million in highly selective Starting Grants from the ERC @erc.europa.eu​. Read: https://ista.ac.at/en/news/e9-2-million-in-eu-grants-for-ista/
@paulschanda.bsky.socialThe ICMRBS conference in Davos has been fantastic. Relaxed atmosphere, top science, great opportunities to connect. I'm happy to be part of the #NMR community, a supportive & friendly crowd. Thanks @icmrbs2026.bsky.social for everything! The (short) bike trip back was a nice way to finish the week.
@paulschanda.bsky.social📢 New preprint:
Experiment-guided AlphaFold3 resolves accurate protein ensembles.
doi.org/10.1101/2025...
AlphaFold3 is incredible, but has crucial limitations: it typically collapses to a single conformation, ignoring the inherent dynamics of proteins. And it can be wrong. Here's a solution. 🧵👇
