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Centre for Structural Systems Biology CSSB

@cssbhamburg.bsky.social

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@rappopto.bsky.socialOct 5, 2026, 5:46 PMReposted by @cssbhamburg.bsky.social

🔬This week at @cssbhamburg.bsky.social, we’re testing #holotomography on real participant samples: from bacteria and biofilms to cells, 3D cultures, tissues, and whole organisms.
✨Our carousel gives a quick technical overview of the method and the @tomocube.bsky.social HT-X1™ Plus.
#LabelFreeImaging

@rappopto.bsky.socialOct 1, 2026, 6:13 AMReposted by @cssbhamburg.bsky.social

🔬 High-res 3D imaging without labels: #holotomography uses refractive index as intrinsic contrast for quantitative imaging of living samples.
Next week at @cssbhamburg.bsky.social , we’ll demo the @tomocube.bsky.social HT-X1™ Plus hands-on with participant samples.
Book your spot: shorturl.at/Pu2U3

@spcembl.bsky.socialSep 30, 2026, 2:56 PMReposted by @cssbhamburg.bsky.social

🔥 New from our group in Protein Science!

We introduce CheMelt, a tool for analyzing thermal & chemical protein denaturation, integrated into the EMBL Hamburg eSPC platform.

📖 Read the paper:
onlinelibrary.wiley.com/doi/10.1002/...

@embl.org @cssbhamburg.bsky.social
@au.dk

#Biophysics #CheMelt

@cssbhamburg.bsky.socialSep 30, 2026, 11:45 AM

During their 2-day visit, our SAB members learned about the latest developments at CSSB, met our newest group leader, and exchanged ideas with postdocs and PhD students during our poster session.

Thank you to all our SAB members for your engagement! @thamlab.bsky.social @oneyrolles.bsky.social

@spcembl.bsky.socialSep 28, 2026, 8:49 AMReposted by @cssbhamburg.bsky.social

What brings clathrin adaptors, phase separation & membrane trafficking together? 🧬🔬

Our new paper in Communications Biology explores just that!

Discover how clathrin adaptors drive LLPS during endocytosis—and what we found 👇

www.nature.com/articles/s42...

@embl.org @cssbhamburg.bsky.social

@cssbhamburg.bsky.socialSep 25, 2026, 1:14 PM

What role do membrane contact sites play in bacterial pathogenesis and infection? To explore this question, 24 PIs from across Germany, representing two scientific communities - lipid biology and infection biology - came together at CSSB. More info:https://t1p.de/xe7u0 @carobarisch.bsky.social

@cssbhamburg.bsky.socialSep 9, 2026, 11:13 AM

The MHH Virology Retreat took place at CSSB last week. Participants had a great time getting to know CSSB and sharing their latest research. Thanks to all who attended! @bosse-lab.bsky.social

@cssbhamburg.bsky.socialSep 7, 2026, 12:19 PM

Researchers from CSSB and the @uwmadison.bsky.social have discovered that a layer of cellular energy regulation lies in proteoforms — unique chemical variants of proteins. A new study reveals how these proteoforms arise through the activity of AMPK.

More Information: t1p.de/orr75

@helmholtzhzi.bsky.socialSep 7, 2026, 7:35 AMReposted by @cssbhamburg.bsky.social

P. aeruginosa kann viele verschiedene Gewebe infizieren. HZI-Forscher Michael Kolbe am @cssbhamburg.bsky.social hat nun mit Kolleg:innen Proteine des Bakteriums strukturbiologisch untersucht & konnte zeigen, wie sie Poren in der Zellmembran des Wirts verursachen.
www.helmholtz-hzi.de/media-center...

@cssbhamburg.bsky.socialSep 4, 2026, 12:43 PM

Congratulations to @deep-dv-for5200.bsky.social social for receiving the 2026 North German Science Award! Congrats to all the scientist who are part of the DEEP-DV team including CSSB group leader Jens Bosse @bosse-lab.bsky.social .

@cssbhamburg.bsky.socialSep 4, 2026, 10:41 AM

Researchers from CSSB's Kolbe group (@uni-hamburg.de, @helmholtzhzi.bsky.social), along with collaborators from Research Center Jülich, EMBL Hamburg, DESY and BIOTECH Thailand have uncovered novel virulence mechansims of phospholipase C from P. aeruginosa.

More info: t1p.de/sbjpq

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