@uhnresearch.ca @uhn.ca

In people with age-related blood stem cell mutations, our study found early pre-fibrosis and inflammatory regions in the bone marrow, that may set the stage for blood cancer development.

The @natimmunol.nature.com study was led by Dr. Anastasia Tikhonova:
www.nature.com/articles/s41...

A new lipid nanoparticle, LC-1, overcame gene editing barriers and efficiently delivered large RNA tools to the preclinical models of liver, lungs, and brain.

The Nature Biotechnology study was led by Dr. Bowen Li @uhn.ca Princess Margaret Cancer Centre:
www.nature.com/articles/s41...

Congratulations to our Senior Scientist Dr. Tak Mak for receiving the German Immunology Prize from the German Society for Immunology!

Learn more about the transformative discovery of T cell receptor here: www.uhn.ca/corporate/Ne...

Congratulations to Dr. @benlok.bsky.social on receiving the Heine H. Hansen Lectureship Award for Small Cell Lung Cancer (SCLC) from @iaslc.bsky.social for his sustained practice-changing contributions in understanding DNA repair mechanisms & improving patient outcomes.
www.iaslc.org/lectureship-...

Our researchers identified a set of 94 regulatory proteins that can help predict survival outcomes and treatment response in triple-negative breast cancer, paving the way for more personalized therapy for patients with this aggressive disease.
www.nature.com/articles/s41...
@uhnresearch.ca @uhn.ca

Congratulations to Dr. Long Nguyen on being named Canada's Top 40 Under 40 by @financialpost.com for leading a research program uncovering how cancer cells evolve, adapt, and develop resistance to treatment, to improve patient outcomes.

@uhnresearch.ca @uhn.ca

Check out our news story here: www.uhnresearch.ca/news/9-16-20...

Finding immune cells that naturally recognize cancer has been a barrier to developing T cell-based therapies. Our study used AI to decode what makes γδ T cells respond to tumour cells, unlocking new therapeutic potentials.
@nature.com : www.nature.com/articles/s41...
@uhnresearch.ca @uhn.ca

Instead of manually counting and drawing boundaries around micronuclei, tiny DNA-containing structures that signal genome instability, we developed an AI-based tool that automates the process and helps researchers study how cells accumulate genetic damage.

www.cell.com/cell-reports...

C2MCI invites you to join us for our upcoming Virtual Seminar Series public lecture with Dr. Nahyun Kwon of Dr. Gang Zheng’s lab @pmresearch-uhn.bsky.social @uhn.ca

➡️ Register today to learn about the application and design of gold nanoclusters for biomedicine: bit.ly/4zRiBmU
#NFRF

Congratulations to Drs. Laura Dawson and Jan Seuntjens on being elected Fellows of the Royal Society of Canada! Their research has advanced precision radiation treatment and improved cancer care in Canada and around the world.
rsc-src.ca/en/about/pub...

Our study reveals a key cause of lasting bone marrow damage after doxorubicin: the chemotherapy activates CD8 T cells to produce interferon-γ, which fuels chronic inflammation and disrupts the bone marrow environment.

doi.org/10.1182/bloo...
@uhnresearch.ca @uhn.ca