@cddpress.bsky.social
SCIENTIFIC JOURNAL group by @SpringerNature Cell Death & Differentiation, Cell Death & Disease, Cell Death Discovery
@cddpress.bsky.social“Targeting common denominators of DNA damage tolerance mechanisms as therapeutic strategy to cope with dynamic phenotypic changes in triple-negative breast cancer cells”
DDT pathway components as exploitable vulnerabilities of #TNBC cells ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“JP-1302 inhibits RNA polymerase I transcription and induces nucleolar stress in cancer cell lines”
A pharmacologically distinct inhibitor of ribosome biogenesis with broader, dose-dependent chromatin-disruptive activity ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“Chondroitin sulfate shapes the unfolded protein response in osteosarcoma to sustain cancer cell survival during ER stress”
Read more about the regulatory and functional relationships between oncofetal CS and #ERStress in #Osteosarcoma ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“nHOTAIRM1 scaffolds ANXA11-dependent assemblies to drive axonal mRNA localization in human motor neurons”
How do #neurons deliver specific mRNAs to distant axons?
This work uncovered how a #lncRNA can regulate mRNA sorting in human #spMNs ⤵️
nature.com/articles/s41...
@cddpress.bsky.socialExplore our October issue: nature.com/cdd/volumes/...
@cddpress.bsky.social“Anthracycline and antimetabolite, trigger distinct resistance mechanisms in TP53mut AML”
Read this latest Correspondence in Cell Death Discovery ⤵️
nature.com/articles/s41...
@cddpress.bsky.social🎗️ Liver Cancer Awareness Month 🎗️
Browse our collection of research papers focused on liver cancer in:
Cell Death & Disease
nature.com/subjects/liv...
Cell Death Discovery
nature.com/subjects/liv...
#LiverCancer #CancerResearch
@cddpress.bsky.social🎗️ Breast Cancer Awareness Month 🎗️
Access our updated collection of breast cancer-related research papers in:
Cell Death & Disease
nature.com/subjects/bre...
Cell Death Discovery
nature.com/subjects/bre...
#BreastCancer #BreastCancerAwarenessMonth #CancerResearch
@cddpress.bsky.social“Efferocytosis triggered proteomic reprogramming of macrophages reveals CD97 as a novel apoptotic receptor”
@mtrost.bsky.social identified CD97 as a novel #Efferocytosis-associated protein ⤵️
www.nature.com/articles/s41...
@cddpress.bsky.social“Galectin-3 restrains T cell-driven inflammation in the testis and epididymis”
This study advances the understanding of the mechanisms underlying immune-mediated male #Infertility ⤵️
www.nature.com/articles/s41...
@cddpress.bsky.social“DDX3X regulates DNA repair pathway choice at double-strand breaks via RNA-DNA hybrid formation”
This work highlights a new mechanism controlling #DNARepair and tumor cell sensitivity to #chemotherapy ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“Hepatitis B virus protein X promotes survival and loss of hepatocyte identity in a differentiated human liver organoid system”
This physiologically relevant organoid model clarifies longstanding questions about the pathogenesis of #HBV-associated #HCC ⤵️
nature.com/articles/s41...
@auscelldeathsoc.bsky.socialReposted by @cddpress.bsky.social(1/6) 🌏International Cell Death Seminar Series - Edition #2🌏 Join us for our second International Cell Death Seminar of 2026, hosted in collaboration with ECDO European Cell Death Organisation and CCD Press. See the flyer below for more information.
@cddpress.bsky.social"MDM2 binds and suppresses RNA polymerase III to restrain the innate immune response to cytosolic DNA"
www.nature.com/articles/s41...
@cddpress.bsky.social“The expanding MDM2 universe”
Fresh off the press: an editorial by Prof. Engeland about the recently uncovered connection between MDM2 and #InnateImmunity ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“Immunoregulatory role of quercetin in lung cancer”
Quercetin exerts potent #Antioxidant, #AntiProliferative, and #Immunomodulatory effects ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“PGC1α-mediated upregulation of PHD2 represses HIF-signaling, limiting prostate cancer progression”
PGC1 represses HIF signaling via ERR-driven EGLN1 transcriptional induction, expanding its #TumorSuppressive role in #PCa ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“Cuproptosis in iron overload hepatocytes”
Copper as a potent and previously underappreciated modifier of iron-induced cellular injury ⤵️
nature.com/articles/s41...
@cddpress.bsky.social“SMC1A is required for fate determinations of human spermatogonial stem cells and male fertility by interacting with YBX1 and stabilizing HMGA2 mRNA via an m5C modification”
Potential genetic markers and therapeutic targets for #NOA ⤵️
nature.com/articles/s41...
@cddpress.bsky.social"ATP synthase subunits e and g are essential for Ca2+ homeostasis and development in Drosophila melanogaster independent of oxidative phosphorylation"
A novel role for ATP Synthase in #Ca2+ homeostasis in #Drosophila ⤵️
nature.com/articles/s41...
