@cp-immunity.bsky.social
Cutting-edge research in immunology from around the world, and commentaries by thought leaders. Cell Press. Posts by Immunity editors.
@davalos.bsky.socialReposted by @cp-immunity.bsky.socialOur study is out in @cp-immunity.bsky.social: Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse. Grateful to lab members, collaborators, funders, reviewers, @kavithascranton.bsky.social www.cell.com/immunity/ful...
@cp-immunity.bsky.socialOnline now: Lymphatic constraint of germinal centers optimizes protective antibody responses
@cp-immunity.bsky.socialOnline now: Single-cell analyses of global cohorts outline determinants of immune aging and link the ratio of GZMK+ to GZMB+ Tem cells to health trajectories
@cp-immunity.bsky.socialOnline now: Microglia-mediated extracellular matrix disruption drives neuronal dysfunction, motor impairments, and sedation following alcohol abuse
@cp-immunity.bsky.socialOnline now: Induced regulatory B cells stably expressing interleukin-10 reverse central nervous system autoimmunity by targeting myeloid cells
@labwaggoner.bsky.socialReposted by @cp-immunity.bsky.socialFunctional evaluation of TCR-pMHC pairs at scale allows in silico TCR reactivity prediction @cp-immunity.bsky.social
www.cell.com/immunity/ful... @schumacher-lab.bsky.social @nkinl.bsky.social
@labwaggoner.bsky.socialReposted by @cp-immunity.bsky.socialNutrient deprivation promotes Th9 cell senescence to compromise persistence, highlighting the potential of targeting ZAK to rejuvenate CAR-Th9 cells for solid tumor therapy @cp-immunity.bsky.social
www.cell.com/immunity/ful...
@wsantus.bsky.socialReposted by @cp-immunity.bsky.socialAire is a cell-intrinsic regulator of natural IgM-secreting cells: Immunity @cp-immunity.bsky.social www.cell.com/immunity/ful...
@cp-immunity.bsky.socialOnline now: Distant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy
@cp-immunity.bsky.socialOnline now: Functional evaluation of TCR-pMHC pairs at scale allows in silico TCR reactivity prediction
@cp-immunity.bsky.socialOnline now: Glucose-deprived tumor microenvironment activates AMP-activated protein kinase to drive adoptively transferred T helper 9 cell senescence
@natrevimmunol.nature.comReposted by @cp-immunity.bsky.socialNEW Highlight of @cp-immunity.bsky.social paper by Xueping Zhu, @carriesokol.bsky.social et al. showing that protease allergens induce mTORC1 activation and mitochondrial remodelling in TRPV1+ peptidergic sensory neurons in the skin.
@cp-immunity.bsky.socialOnline now: Aire is a cell-intrinsic regulator of natural IgM-secreting cells
@cp-immunity.bsky.socialOnline now: Influenza vaccine format mediates distinct cellular and antibody responses in human immune organoids
@cp-immunity.bsky.socialOnline now: Microglia with distinct origins and non-canonical phenotypes coexist within the border-like niche of the brain’s circumventricular organs
@maurogaya.bsky.socialReposted by @cp-immunity.bsky.socialVery happy to see Sergio's work out. Super proud of him! And thanks to our many collaborators. I hope you enjoy it as much as we do!
@stemcellsciencenews.comReposted by @cp-immunity.bsky.socialA new study in @cp-immunity.bsky.social reveals that an ILC2-driven serotonergic circuit contributes to asthma pathophysiology and highlights serotonergic signaling as a therapeutic target!
Read more about the exciting findings here🫁: https://bit.ly/4xJAfrj
@cp-immunity.bsky.socialOnline now: Targeting a site of vulnerability on circumsporozoite protein inhibits Plasmodium vivax malaria infection
@carriesokol.bsky.socialReposted by @cp-immunity.bsky.social1/ Why can you encounter an allergen repeatedly before becoming allergic to it? In our new @cp-immunity.bsky.social paper, led by the wonderful Xueping Zhu, we asked whether the sensory neurons that first detect allergens might carry a record of earlier exposures. 🧵
@cp-immunity.bsky.socialOnline now: Germinal center interleukin-4 microniches drive tissue divergence of IgE memory B cell responses
