Our new paper is out @jcellsci.bsky.social 🧬✨ doi.org/10.1242/jcs.... @ynagata.bsky.social et al combined single-nucleosome imaging + Fucci probes. H2B-Halo motion stays nearly constant from G1 to G2. H3.3-Halo euchromatin nucleosomes are more mobile, but their motion also stays nearly constant.

1/ Our paper, “Enhancer binding kinetics explain transcription factor hub formation,” is now published! Here we set out to understand why transcription factors form bright clusters or “hubs” in the nucleus, and whether those hubs actually control gene activity.
tinyurl.com/38uf8348

Is euchromatin really “open”? 🧬 Using super-resolution imaging🔬 our new study @natgenet.nature.com reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing for proper transcriptional insulation🚧 🔗
www.nature.com/articles/s41... (1/2)

Happy to share that this paper is now published in Nature Genetics!

Grateful to everyone who supported this work throughout this long journey. I’m proud to see it out!
www.nature.com/articles/s41...