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Thibaut Brunet

@thibautbrunet.bsky.social

3k Following5.8k Followers

Evolutionary cell biology / evolution of morphogenesis / animal origins / choanoflagellates @institutpasteur.bsky.social

https://research.pasteur.fr/en/team/evolutionary-cell-biology-and-evolution-of-morphogenesis/

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@thibautbrunet.bsky.socialOct 11, 2026, 6:43 PM

Oui

@paveltomancak.bsky.socialOct 11, 2026, 5:45 PMReposted by @thibautbrunet.bsky.social

Vive la France

@evgenii-protasov.bsky.socialOct 10, 2026, 3:59 PMReposted by @thibautbrunet.bsky.social

The archaeon Sukunaarchaeum mirabile, associated with dinoflagellates, has a genome of only 238 kbpđŸ§ŹđŸ€Ż
#archaea #symbiosis #eukaryotes #protists #MicroSky
@currentbiology.bsky.social
www.cell.com/current-biol...

@jgschraiber.bsky.socialOct 10, 2026, 11:38 PMReposted by @thibautbrunet.bsky.social

I'm not a software engineer but in my experience as a computational scientist, most individual parts of my job are basically automated. The thing that's not there (yet) is stringing them together in an interesting way. Then again I've never tried launching 10k agents at a problem!

@thibautbrunet.bsky.socialOct 10, 2026, 8:35 PM

Terence Tao is great, but also, we don’t understand how paracetamol works (the same for: propofol, lithium for bipolar disorder
)

@harmitmalik.bsky.socialOct 10, 2026, 7:44 PMReposted by @thibautbrunet.bsky.social

Most animal species pack sperm DNA with protamines instead of histones. Protamines are essential for male fertility. They are among the fastest-evolving genes in animals. That makes little sense. We think we know why, in a new paper led by @ching-hochang.bsky.social. www.science.org/doi/10.1126/...

@ewanbirney.bsky.socialOct 10, 2026, 5:23 PMReposted by @thibautbrunet.bsky.social

The @embl.org PhD programme closes in 48 hours - you still have time to rush in an application if you are a science, maths or computer science undergraduate wanting to do a PhD in one of the world's leading biology and AI institutes

www.embl.org/about/info/e...

@itaiyanai.bsky.socialOct 10, 2026, 2:30 PMReposted by @thibautbrunet.bsky.social

1. CRISPR came from basic research on bacteria. 2. Optogenetics started with a discovery in algae. 3. The GFP protein comes from jellyfish. The biggest breakthroughs all trace to scientists following their curiosity, and this is one huge reason why we must keep funding basic research!

@thibautbrunet.bsky.socialOct 10, 2026, 11:13 AM

J’ai entendu cela aussi ! Sous une forme encore plus Ă©trange : la Chine n’aurait *jamais dans son histoire* tentĂ© de conquĂ©rir ses voisins (le Vietnam, la CorĂ©e, la Mongolie
 ont tous fait l’objet de guerres de conquĂȘte rĂ©pĂ©tĂ©es). J’imagine que plus c’est gros, plus ça passe.

@micromotility.bsky.socialOct 9, 2026, 3:21 PMReposted by @thibautbrunet.bsky.social

Please enjoy this new offering from the lab: we discover that #excavates - ancient flagellate lineages with a voracious appetite for bacteria - change their behaviour depending on the availability of said prey!

Preprint here: www.biorxiv.org/content/10.6...

#protistsonsky

@christlet.bsky.socialOct 9, 2026, 2:35 PMReposted by @thibautbrunet.bsky.social

Nikon Small World does the right thing

@thibautbrunet.bsky.socialOct 9, 2026, 2:13 PM

One never knows with Trump, but he seems to only know of the meaning of "artificial" as "fake" (antonym: "real"), and not really as "man-made" (antonym: "natural"). He thinks AI is "real" intelligence and thus not "artificial".

@thibautbrunet.bsky.socialOct 9, 2026, 12:58 PM

The etymology of the color "sepia" is my new favorite etymology (h/t Wikipedia)

Wikipedia screenshot: Sepia is a reddish-brown color, named after the rich brown pigment derived from the ink sac of the common cuttlefish Sepia. The word sepia is the Latinized form of the Ancient Greek word ÏƒÎ·Ï€ÎŻÎ± (sēpĂ­a), meaning cuttlefish.
@nicolasberrod.bsky.socialOct 8, 2026, 7:40 AMReposted by @thibautbrunet.bsky.social

Info Le Parisien : Kyan Khojandi est le nouveau parrain du Pasteurdon, qui vise 3 millions d'€ de dons cette annĂ©e.

"En tant que comique, je ne sauve pas des vies. Mais si je peux apporter un coup de projecteur Ă  mon humble niveau, tant mieux !"

1/4

www.leparisien.fr/so...

@thibautbrunet.bsky.socialOct 9, 2026, 12:55 PM

This kind of nuanced take addresses the concerns of both sides... which I hope/feel are anyway less polarized irl than on social media

@thibautbrunet.bsky.socialOct 9, 2026, 12:55 PM

I found this proposal by @caseywdunn.bsky.social et al interesting: distinguishing LLMs "off the data path" (used to produce code one can verify/use; usually fine) vs "on the data path" (less verifiable, potentially problematic) www.cell.com/patterns/ful...

(A) The LLM lives off the data path: the assistant produces code that can be versioned and archived, and the code itself sits on the path.
(B) The LLM lives on the data path: the model call is itself a node, and reproducing the workflow requires the original runtime.
@biologists.bsky.socialOct 9, 2026, 9:00 AMReposted by @thibautbrunet.bsky.social

Applications close on 23 October for funded ECR places at our Workshop on Bridging Scales and Disciplines to Understand Robust Development, 18-21 April 2027 organised by Mauricio Rocha Martins @rocha-lab.bsky.social and Giulia Paci @giuliapaci.bsky.social

Apply at biologists.com/workshops/ap...

Bridging Scales and Disciplines to Understand Robust Development
Date: 18-21 April 2027

Location: Buxted Park, East Sussex, UK

Organisers: Mauricio Rocha Martins and Giulia Paci
@plantophagy.bsky.socialOct 9, 2026, 9:02 AMReposted by @thibautbrunet.bsky.social

European Union, Marie Curie, EMBO should triple postdoc fellowships! www.nature.com/articles/d41...

@hannamariahakkinen.bsky.socialOct 9, 2026, 9:48 AMReposted by @thibautbrunet.bsky.social

How do long-lived multipotent stem cells cope with mechanical stress in vivo?

We found that neural crest cells are protected from mechanical stress during migration in confined tissue environment.
www.nature.com/articles/s41...

@thibautbrunet.bsky.socialOct 9, 2026, 10:15 AM

How fast can speciation be? In less than 100 years, certain strains of lab mice have already (partly) lost the ability to hybridize with each others. The molecular mechanism has just been worked out - read below for a genetics detective story âŹ‡ïž

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