Now that we have moved coasts, I am thrilled to share that the ChromEvo (Raman) lab is officially open at UMass Boston 🎉
We ask how CHROMatin EVOlution leads to functional innovation and we are hiring at multiple levels. Read on and share with folks who maybe interested
chromevoramanlab.github.io
@ching-hochang.bsky.social
@ching-hochang.bsky.social
Now, the next chapter!
Our lab at the Institute of Molecular Biology, Academia Sinica in Taiwan, is fully up and running. We are actively recruiting passionate researchers at all levels to tackle bold ideas in cell biology, chromosome architecture, and evolution:
I also want to remember the late Meng-Chao Yao. His wisdom, kindness, and unwavering encouragement during my postdoc years and faculty job searches meant a lot to me. I am deeply grateful for his mentorship.
This work would not have been possible without incredible mentors and colleagues. Huge thanks to Harmit Malik, Amanda Larracuente, Yukiko Yamashita, Benjamin Loppin, Barbara Wakimoto, Steve Henikoff, Kami Ahmad and many people for invaluable feedback, insights, and discussions over the years.
Thrilled to share that our paper is finally out in Science Advances!
🔗 www.science.org/doi/10.1126/...
TL;DR: A Drosophila protamine acts as shields resolving conflict between X and Y chromosomes. Disruption unleashes meiotic drive that kills X-bearing sperm and skews progeny sex ratios. 🪰🧬ᯡ
Research is full of uncertainty, but every once in a while, nature works out exactly as you hypothesized.
In 2019, while finishing my PhD, I pitched a bold idea in an email to @harmitmalik.bsky.social (below). Seven years later, it feels surreal to see that hypothesis become empirical reality. 🧵👇
