I am very pleased that our tr-SFX + tr-XES work on the isopenicillin N synthase reaction has been published in Nature Catalysis. Thanks to the many wonderful collaborators! #XFEL; #DynamicStructuralBiology; #DiamondLightSource; #LCLS

www.diamond.ac.uk/Science/Rese...

www.nature.com/articles/s41...

9-Oct-2026
Ingenious ‘molecular movie’ finally reveals how penicillin is made

In the new study, #Oxford researchers and others have used X-ray free-electron lasers #XFEL to observe the #enzyme isopenicillin N synthase, or IPNS as it converts its linear #peptide substrate into the ring system of […]

🔬 Join Prof. Martin Beye (WG2 leader) for the XFELLOWs seminar “Towards femtochemistry X-ray studies of catalysis on surfaces under operando.”

📅 9 Sept., 5 pm Europe / 11 am ET / 8 am PT
💻 Online

Register: mit.zoom.us/meeting/regi...

#XFEL #Catalysis