🧬Could HLA-DQ biology hold clues to kidney transplant outcomes? New findings highlight associations between HLA-DQ heterodimers and graft survival, opening new avenues to better understand HLA biology in #transplantation. #TXPforAll #OpenAccess tinyurl.com/dckpfmsd

🫘A new synthetic solution for kidney preservation? Omnisol maintained more stable perfusion, near-constant pH and better tissue morphology than Belzer MPS during 24 h HOPE in porcine kidneys. #TXPforAll #Transplantation #OpenAccess tinyurl.com/297278e3

This review explores the potential of combining donor and recipient genetics to advance precision transplantation using polygenic risk scores, while highlighting the key challenges to clinical implementation. #TXPforAll #Transplantation tinyurl.com/2tm4c7ca

Can the graft’s DNA tell us how it will perform? This study shows that cell-free DNA—particularly mitochondrial cfDNA—measured during machine perfusion is associated with post-transplant graft outcomes. #TXPforAll #Transplantation tinyurl.com/mrzhsv47

🌍 A global survey across 64 countries highlights the scale and complexity of international travel for organ transplantation (ITOT) and the need for stronger data, governance and equitable access. #TXPforAll #Transplantation #Organdonatio tinyurl.com/2z379usk

This study shows that RSV vaccination induces robust functional humoral immunity in immunocompromised patient groups, with kidney transplant recipients showing the lowest levels. #TXPforAll #Transplantation #Vaccination tinyurl.com/wrsxc7dp

This review by Diebold et al. explains how natural killer (NK) cells contribute to kidney allograft injury beyond their classic role in innate immunity. #TXPforAll #Transplantation #Immunology tinyurl.com/yccxurnk

Immune Checkpoint Inhibitor therapy showed a trend toward longer overall survival vs standard chemotherapy, with low rates of rejection and allograft loss. #TXPforAll #Transplantation #OpenAccess tinyurl.com/29ksmjbx

💊 Letermovir vs valganciclovir: a promising alternative for CMV prophylaxis! #TXPforAll #Transplantation #OpenAccess tinyurl.com/bdzb4xvr

This review paper explains why solid organ transplant recipients are at increased risk of HPV-associated anal cancer. #TXPforAll #Transplantation #Infection tinyurl.com/yeu3b3vv

This study shows that weight ratio offers a simple real-time tool to flag size-mismatched grafts and identify recipients who may need closer perioperative monitoring. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4v36k59c

🫁 Promising findings in lung transplantation: S1PR1 activation with CYM5442 during EVLP reduced pulmonary edema, lung weight gain, pressures, and inflammatory mediator release while preserving endothelial integrity. #TXPforAll #Immunology #Transplantation tinyurl.com/36jts4m3

Exciting Results: In 204 HCV-negative recipients of kidneys from HCV-viremic donors, 7-day sofosbuvir/velpatasvir prophylaxis resulted in 100% overall SVR12 after retreatment, with excellent 1-year patient and graft survival. #TXPforAll #Transplantation tinyurl.com/3m32prtb

Multiple renal arteries? No longer a contraindication to robotic kidney transplantation! #TXPforAll #Transplantation #OpenAccess tinyurl.com/4b5z93w3

Could 10°C be the new sweet spot for kidney preservation is discussed in this paper by Francisco Calderon Novoa et al. #TXPforAll #Transplantation #OpenAccess tinyurl.com/67fzfyc2

This review explains how sexual intercourse exposes females to partner-derived MHC and minor histocompatibility antigens, including sperm-specific antigens (SPAGs. #TXPforAll #Transplantation tinyurl.com/3trk7zz2