@thewoolab.bsky.socialJoin us in Banff ๐จ๐ฆ ๐๏ธnext February for the @keystonesymposia.bsky.social
for Induced Proximity and Targeted Protein Degradation! Registration is still open, with the scholarship deadline approaching this week on Oct 14 ๐ซก
keysym.us/KSProximity27 #KSProximity27 #TPD #MolecularGlues #ChemicalBiology
@stephanhacker2.bsky.socialAre PROTACs that engage target proteins in an irreversibly covalent manner viable?
A new Nature Communications paper by the groups of Jin Wang and Xiaoli Qi now convincingly shows potent BTK degradation employing an irreversible BTK ligand.
@kiborgkazakh.bsky.social
@led3hub.bsky.socialNew @biorxivpreprint.bsky.social from the group of @sebastianpomplun.bsky.social of our LED3 hub!
๐๐๐๐๐๐๐๐๐: ๐๐ง ๐๐ฎ๐ญ๐จ๐ฆ๐๐ญ๐ข๐จ๐ง ๐๐ฅ๐๐ญ๐๐จ๐ซ๐ฆ ๐๐จ๐ซ ๐๐๐ฉ๐ข๐ ๐๐ข๐ญ-๐ญ๐จ-๐๐๐ ๐ซ๐๐๐๐ซ ๐๐ข๐ฌ๐๐จ๐ฏ๐๐ซ๐ฒ
www.biorxiv.org/content/10.6...
#ChemBio #ChemSky #DrugDiscovery #Degrader #TPD
@leidenscience.bsky.social
@inee.orgโ๏ธHow can funders support #education in #Yemen?
โ
Provide flexible, multiโyear funding
โ
Prioritize funding for teacher salaries and #TPD
โ
Invest in school feeding programs
โ
Fund alternative, accelerated, and non-formal education
& more!
Learn more at โก๏ธ inee.org/crisis-spotlight/yemen
@lsajournal.orgNew research shows that an N-terminal dTAG cassette alters RAF1 scaffold function in KRAS-driven lung cancer models before degradation, underscoring the importance of validating tagged proteins.
#CancerResearch #TPD
www.life-science-alliance.org/content/9/12...
@anonturk.bsky.social
@conway-group.bsky.socialOur paper reporting the discovery of a selective molecular glue degrader of the transcription factor FIZ1 is now online in @jacs.acspublications.org! This work was a great collaboration with Heeseon An's lab at @mskcancercenter.bsky.social.
Read more here: pubs.acs.org/jacsat/artic...
