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@cddpress.bsky.socialOct 9, 2026, 10:15 AM

“Targeting common denominators of DNA damage tolerance mechanisms as therapeutic strategy to cope with dynamic phenotypic changes in triple-negative breast cancer cells”

DDT pathway components as exploitable vulnerabilities of #TNBC cells ⤵️
nature.com/articles/s41...

@cancers-mdpi.bsky.socialOct 9, 2026, 7:32 AM

🧩Editor’s Choice

#Immunotherapies for #BreastCancer: From Checkpoint Inhibition to Emerging Cellular Therapies
🧑‍⚕️by Ismini Tsagkaraki, Isaac Gannon et al.
🏥 @royalberkshospital.bsky.social, @uclh.bsky.social
📈6 citations
Link🔗 www.mdpi.com/2072-6694/18...

#TNBC #ICIs #CART #CARNK

Figure 1. Different immunotherapeutic approaches targeting breast cancer. Antibody-based therapies, Tumour Infiltrating Lymphocytes, TCR-Targeting T-cells and CAR-T cell therapies are highlighted here. Advantages and disadvantages of each modality are highlighted with either a green check mark or a red cross respectively. In the middle, the most promising antigenic targets for TCR and CAR-T cell therapies are presented.
@stskorpiiia.bsky.socialOct 8, 2026, 8:32 PM

Skorptober Day 8 - Sorcery ✨

featuring @crystallizedtwi.bsky.social ‘s #tnbc au Shock (who I would 💀 for) 😩🖤

#skorptober #drawtober #digitalart #tnbc #thenightmarebeforechristmas #artsky #newart #shock #illustration

@ashzelda.bsky.socialOct 8, 2026, 1:43 PM

My fav spooky throwback. 💀💙

#tnbc #nightmarebeforechristmas #tnbccosplay #tnbcbarrel

@leilabella0505.bsky.socialOct 8, 2026, 1:29 AM

Jack and sally finally had a kid and it’s a boy #tomodachilife #tomodachilifelivingthedream #thenightmarebeforechristmas #tnbc #miis

@sigtrans-sttt.bsky.socialOct 1, 2026, 7:42 AM

A multitarget strategy may help address #TNBC heterogeneity.

Opti-hTIF1γ suppresses β-catenin, TGFβ and STAT3 signaling while downregulating CD47 and CXCL5, enhancing #macrophage phagocytosis and #antitumoractivity.
#TumorMicroenvironment #CancerBiology
#STTT #OpenAccess: doi.org/10.1038/s413...

Transcriptional intermediary factor 1 gamma-based multitarget gene therapeutic strategy for triple-negative breast cancer
@eortc.orgSep 30, 2026, 2:56 PM

📢 A new IMMUcan publication in Cell Reports Medicine sheds light on response to chemo-immunotherapy in advanced #TNBC and highlights the contribution of the EORTC-1553-SPECTA platform to translational cancer research.

Read more: spectaplatform.org/2026/09/30/i...

#IMMUcan #SPECTA

@sigtrans-sttt.bsky.socialSep 30, 2026, 8:30 AM

Quiescent #BreastCancer stem-like cells can reawaken in #TNBC.

New study in #STTT identifies an ENO1–lactate–H4K12la feedback loop that upregulates PCNA to activate qsBCSCs, revealing a metabolic–epigenetic axis linked to tumor growth.

#OpenAccess: doi.org/10.1038/s413...

Glycolytic enolase 1-induced H4K12 lactylation activates quiescent breast cancer stem-like cells in triple-negative breast cancer
@sigtrans-sttt.bsky.socialSep 26, 2026, 3:45 PM

Single-cell #Multiomics reveals that #TNBC-derived #Exosomes reshape T cells through regulatory and dysfunctional states, #miRNA-mediated immune suppression, and distinct γδ and αβ TCR clonotypic expansions.

#STTT #OpenAccess: doi.org/10.1038/s413...

Single-cell multiomics reveals exosome-mediated reprogramming and clonotypic remodeling of T cells in triple-negative breast cancer
@mdpipharma.bsky.socialSep 23, 2026, 10:16 AM

🔬 New #Cover #Story! Multi-omics analysis uncovers the mechanism of action of a multifunctional #nanosystem against #TNBC—showing promise as an #antitumoral treatment.

Read more papers in Volume 18 - Issue 8 👇
brnw.ch/21x5Sc0

👉 brnw.ch/21x5SbZ
#TNBC #Nanomedicine #MultiOmics #Cancer

@cheshirepins.bsky.socialSep 20, 2026, 11:35 PM

Next batch~
🔗⬇️

#stolitz #helluvaboss #akusai #kingdomhearts #tnbc #thenightmarebeforechristmas #lockshockandbarrel #ibgame #garry

A print of Stolas and Blitz, avoiding each otherA print of Saix getting up in Axel's faceA print of Lock, Shock, and Barrel in winter outfits. Shock is admiring a string of Christmas lights, while Barrel is staring in horror at the giant snowball Lock is about to gleefully lob in Shock's direction A print of Garry from Ib, surrounded by dolls and falling rose petals
@genesndiseases.bsky.socialSep 20, 2026, 3:06 PM

Targeting mitochondrial vulnerabilities could improve #TNBC treatment.
This review shows how altered #MitochondrialDynamics and metabolism drive tumor growth and #chemoresistance, highlighting new therapeutic strategies.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

@cheshirepins.bsky.socialSep 18, 2026, 11:05 PM

Batch 3 of prints~♡
Links to prints below!

#alexaniel #atdd #amnesiathedarkdescenr #lockshockandbarrel #thenightmarebeforechristmas #tnbc #kingdomhearts #joshneku #twewy #theworldendswithyou

Alexander and Daniel from Amnesia, dancing together in front of the large window in the back hall.Lock, Shock, and Barrel as teenagers, in swimsuits, riding in a floaty shaped like the vampire duck. Barrel is trying to disrupt the flow of the floaty while wearing a shark headband, and Shock is yelling at him while sitting in Lock's lap.Axel, Roxas, and Xion, all in a happy embraceJoshua and Neku after just waking up, Joshua has his hands on him and is whispering nice things to him in the morning calm.
@mlp410nightcore.bsky.socialSep 17, 2026, 7:56 PM

Hi Everyone!! Here is Blossom Love AU next gen moodboard #46. Credit goes to Selenaede for the base I used while I take credit for my art and the Blossom Love AU. I hope you guys like this, have a beautiful day and always believe in yourselves!!! #MLP #TNBC #Undertale

www.tumblr.com/mlp410nightc...

@mdpipharma.bsky.socialSep 16, 2026, 10:12 AM

@microbesinfo.bsky.social

🎯 Carrier-free curcumin NPs + TA/Fe(III) coating = triple therapy for TNBC. Chemo + photothermal + ferroptosis in one nanodrug. High loading, NIR-triggered, 4T1 validated.

📌 www.mdpi.com/1999-4923/17...
#TNBC #Nanomedicine #Ferroptosis #CancerTherapy

@cedarssinaicancer.bsky.socialSep 15, 2026, 10:30 PM

Do you have metastatic triple negative breast cancer #TNBC that has grown or spread after treatment? You may be eligible for the #YUANTNBC clinical trial. Follow the link below or call (414)-314-0471 to learn more.

clinicaltrials.cedars-sinai.edu/view/IIT2022...

@medchemexpress.bsky.socialSep 15, 2026, 9:46 AM

💊 #TNBC in 2026: New hope through #TROP2 -directed ADCs, including Datroway(datopotamab deruxtecan) and Trodelvy(sacituzumab govitecan), alongside immunotherapy and biomarker-driven strategies.
🚀What new vulnerabilities can we target? MCE supports breast cancer research toward the next breakthrough.

@lapinamer.bsky.socialSep 12, 2026, 4:34 PM

My TNBC oc, Hodge. He’s a ragdoll.
No relation to Sally.

His TH: toyhou.se/17887723.hodge

#tnbc #nbx #ragdolloc #oc #nightmarebeforechristmas

A nightmare before Xmas ragdoll oc leans against a brick structure. His shirt and jacket are stitched with mismatched fabric. His pants are ripped. His skin is stitched with different tones and his hair is red,black, and white split.
@myesmo.bsky.socialSep 11, 2026, 1:15 PM

#MAP2026: Latest #ClinicalResearch in #TNBC identifies potential novel drivers of chromosome instability linked to immune evasion and #biomarkers of early recurrence post #chemotherapy, expanding knowledge of this aggressive cancer. #ESMODailyReporter:https://ow.ly/lCm550ZMxtZ

@currentmedscience.bsky.socialSep 11, 2026, 7:00 AM

AR-positive #TNBC offers a vital target, but single-agent anti-AR therapies hit steep clinical hurdles. This review outlines how combining AR antagonists with other therapeutic strategies overcomes resistance. #medsky

To read: doi.org/10.1007/s115...

#currentmedicalscience #Oncology

Current Status and Advances in Anti-Androgen Therapy for Triple-Negative Breast Cancer