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@fabmusacchio.bsky.social Sep 20, 2026, 5:03 PM

New paper by @masahironakano.bsky.social , @casewell.bsky.social & @clopathlab.bsky.social who show that planning-like L/R #ThetaSequences in #hippocampus can arise from #MEC dynamics and #Bayesian decoding. Take home: Not every future-like sweep is necessarily planning.

#Neuroscience #CompNeuro

Diagram showing alternating MEC and HPC pathways. Labels include MEC, HPC, Place cells, decoding, and Theta phase. Scale reads 0.2 m.

FIGURE 1 | Modeling left–right MEC sweeps reveals planning-like alternation in hippocampal activity. (

Brain activity graphs labeled HOC and MEC with alternating patterns. Panels show time lags and cell groups. Text reads: "Synchronized left-right alternation in MEC and hippocampus during outbound trials at the center arm".

FIGURE 2 | Simultaneous MEC–hippocampal recordings reveal consistent coupling and left–right alternation at the T-maze decision point.

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