The crystals are characteristically black by Jones methenamine silver stain(C).

The crystals are characteristically black by Jones methenamine silver stain(C).
In the native kindney, this finding is most commonly seen in cryoglobulinemic vasculitis (which was the case for this patient). The differential diagnosis would include other forms of vasculitis such as ANCA-associated diseases.
#TeachingPoints #kidneypath #renal #pathology
This photomicrograph shows an artery with intimal edema and inflammation in a renal biopsy from a 56 year old male with renal failure and nephrotic-range proteinuria. The patient's serologic work-up revealed evidence of an HCV infection and a positive..
#TeachingPoints #kidneypath #renal #pathology