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Y@yaowu1960.bsky.socialOct 10, 2026, 12:01 PM

Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu β€” Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology

Y@yaowu1960.bsky.socialOct 9, 2026, 12:01 PM

Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu β€” Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology

Y@yaowu1960.bsky.socialOct 8, 2026, 12:01 PM

Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu β€” Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology

Y@yaowu1960.bsky.socialOct 6, 2026, 12:01 PM

Biologists: what makes many parts one living system?
This theoretical framework examines boundaries and relations. Which assumption would you test?
Yao Wu β€” Independent Researcher
doi.org/10.5281/zeno...
#Biology #SystemsBiology

@royalsocietypublishing.orgOct 5, 2026, 11:01 AM

New #JRSocInterface research uses computer modelling to reveal how rhythmic pumping and valves in cervical lymphatic vessels work together to drain waste from the brain, offering insights that could help inform future treatments doi.org/10.1098/rsif... | #Bioengineering #Biomechanics #SystemsBiology

@csbj.orgSep 28, 2026, 8:40 PM

πŸ”— Graph Topology Reframes the Coherence of Cell-State Manifold Inference under Heterogeneous Single-Cell Observations. doi.org/10.34133/csb...

πŸ“š CSBJ - A Science Partner Journal: spj.science.org/journal/csbj

@csbj.org #scRNAseq #SingleCellOmics #Transcriptomics #SystemsBiology #CellBiology #Omics

Graph Topology Reframes the Coherence of Cell-State Manifold Inference under Heterogeneous Single-Cell Observations. Computational and Structural Biotechnology Journal (CSBJ). DOI: https://doi.org/10.34133/csbj.0087 CSBJ - A Science Partner Journal: https://spj.science.org/journal/csbj
@fds3rd.bsky.socialSep 26, 2026, 6:01 PM

Bacteria against Mutants
#StemCells #SystemsBiology #Viruses #Microorganisms #Evolution #Development

@fds.wsocial.euSep 26, 2026, 6:01 PM

Bacteria against Mutants
#StemCells #SystemsBiology #Viruses #Microorganisms #Evolution #Development

@royalsocietypublishing.orgSep 19, 2026, 9:00 AM

New research from #JRSocInterface: Cycling cadence selections at different saddle heights minimize muscle activation rather than energy cost doi.org/10.1098/rsif... | #Biomechanics #Biophysics #SystemsBiology

@alicefrolov.bsky.socialSep 18, 2026, 5:01 PM

Cell-fate partitioning after senescence induction: modeling SASP-driven escape trajectories

#CellularSenescence #SASP #CellCycleReentry #SenescenceEscape #TumorSuppression #NFkBSignaling #SystemsBiology #ComputationalCellBiology

Cell-fate partitioning after senescence induction: modeling SASP-driven escape trajectories I am sharing a data visualization that formalizes an increasingly discussed but underappreciated phenomenon in the senescence literature: the capacity of a subpopulation of arrested cells to re-enter the cell cycle rather than remaining stably arrested or undergoing clearance. The figure, titled "Cell-fate partitioning after senescence induction," uses a bidirectional flow trajectory (streamgraph-style stacked area) to render the temporal redistribution of an initial senescent-induced cohort across three terminal or quasi-terminal states over a 30-day window: stable arrest, apoptotic clearance, and senescence escape. The subtitle emphasizes that these are simulated dynamics, not empirical measurements; the parameterization is literature-grounded, calibrated to reported ranges for p16INK4a/p21CIP1 durability, SASP factor accumulation kinetics, and escape frequencies observed in oncogene- and therapy-induced senescence models. The streamgraph format is deliberate. Because escape is a flux phenomenon rather than a static endpoint, the bidirectional banding captures net transitions between compartments, including the small but non-negligible reflux from a metastable arrested state back into proliferation. The simulation encodes a positive-feedback term whereby paracrine and autocrine SASP components β€” principally IL-6, IL-8, and other NF-ΞΊB-dependent secreted factors β€” lower the effective barrier to CDK reactivation in cells with attenuated tumor-suppressor signaling. The escape band consequently widens after the SASP matures, roughly days 8 to 15 in this parameterization, consistent with the delayed secretory phenotype. I would welcome critique on the transition-rate assumptions, particularly the coupling coefficient between SASP intensity and escape probability, which remains poorly constrained empirically.
@pablonavarrolab.bsky.socialSep 17, 2026, 12:26 PM

🧬 How do cells remember?

Join us in beautiful Baeza πŸ‡ͺπŸ‡Έ for Transcriptional Memory in Health and Disease, 20–22 October.

πŸ’₯ Young scientists: €250, including meals!

πŸ“’ Deadline extended to 27 September β€” you can do this!

www.unia.es/estudios-y-a...

#Epigenetics #Chromatin #SystemsBiology

@fds.wsocial.euSep 15, 2026, 6:53 PM

A Broken Heart: Two Types of Scars, Two Paths to Healing
#Bioinformatics #ComputationalBiology #SystemsBiology #MolecularBiology #CellBiology #Disease #Drugs #Diagnostics

@fds3rd.bsky.socialSep 15, 2026, 6:53 PM

A Broken Heart: Two Types of Scars, Two Paths to Healing
#Bioinformatics #ComputationalBiology #SystemsBiology #MolecularBiology #CellBiology #Disease #Drugs #Diagnostics

@larsjuhljensen.bsky.socialSep 15, 2026, 11:32 AM

A video on the STRING version 12.5 update: cleaner functional association network thanks to improved text mining and a new directed regulatory network!
youtu.be/tTf_aIE8Wxw
#bioinformatics #networkbiology #systemsbiology #textmining

@drbattlefisher.bsky.socialSep 13, 2026, 1:30 AM

Latest manuscript in Frontiers in Systems Biology-Sept 2026- #systemsbiology #systemsscience #networkscience #socialnetworks #publichealth #systemsthinking

@csbj.orgSep 11, 2026, 5:33 AM

πŸ“’ Call for Papers: Quantum Immunology and the Dynamic Architecture of Immune Systems

⏳ Submission Deadline: 30 November 2026

πŸ”— Submit your work: spj.science.org/journal/csbj...

@csbj.org #CallForPapers #QuantumImmunology #QuantumBiology #Immunology #SystemsBiology #Biophysics #QuantumScience

The Quantum Biology and Biophotonics section of CSBJ (A Science Partner Journal) is inviting submissions for its upcoming Special Issue: β€œQuantum Immunology and the Dynamic Architecture of Immune Systems” For more information and submission guidelines, please visit: https://spj.science.org/journal/csbj/qbio
@julipereto.bsky.socialSep 10, 2026, 3:56 PM

How engage public with very complex scientific issues: the point of view of teachers, researchers, philosophers or artists @i2sysbio.es #10years #systemsbiology #synbio

@dzunkovam.bsky.socialSep 9, 2026, 4:55 PM

Today, our institute @i2sysbio.es has kicked off the 3 days symposium on #systemsbiology

@parmvir.comSep 7, 2026, 11:00 AM

Our next #MathBioNexus event is up on the Cassyni platform. Use the link to RSVP and hear from Dr. Fred Adler about "Cells, bureaucracy and corruption".
cassyni.com/events/S1zv5....
Of particular interest to anyone in:
#SystemsBiology
#EvolutionaryBiology
#CancerBiology

@smbmathbiology.bsky.social

Text reads: MathBioNexus Cells, breaucracy and corruption. On Sep 23rd at 1PM EDT. Link to cassyni.com/s/mathbionexus. In the top right is the front page of the Bulletin of Mathematical Biology and underneath it a QR code.In the bottom left is a box containing a headshot of Fred Adler and to his left are two images. On top is an image of Max Weber with his name in the top left corner. In the bottom left it says "Theory of Bureaucracy".