SpikeSSL is a new universal spike inference framework for two-photon calcium imaging that addresses poor cross-indicator generalization by replacing generic temporal regressors with bidirectional IIR…

#spikeinference #calciumimaging #opensourceai #neuroscience
https://arxiv.org/abs/2610.11456

Researchers developed the universal SpikeSSL framework, which uses bidirectional state-space layers to improve spike inference accuracy across diverse calcium indicators.

#SpikeInference #CalciumImaging #StateSpaceLayers