🎥 #AgingShort:
Abstract #Video about the #Research paper, "Slowing intervertebral disc aging in mice through long-term systemic treatment with the senolytic BCL-2/BCL-xL proteolysis targeting chimera (PROTAC) 753b.” @pittdeptofmed.bsky.social

🔗 https://bit.ly/44SQzJB

#Aging #Senolytics #OA

Improving cancer therapy may depend on exploiting #TumorSenescence.
This study introduces #MultiOmics SenScore to predict drug response and identify targets for more effective combination treatments. #senolytics
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

✅ Read our #blog post about the #research paper "Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease."

#Summary ⬇️
https://bit.ly/4vOnx8W

#aging #alzheimers #senolytics #oa #summary #publishing

🔬 COPD lungs may age 10-20 years faster due to oxidative stress. With no current drugs targeting the COPD inflammatory pattern, Prof. Barnes highlighted #senolytics (like Bcl-xL inhibitors) as potential therapies to clear senescent cells. 💊 #RespiratoryMedicine #CellularSenescence

🔬 COPD lungs may age 10-20 years faster due to oxidative stress. With no current drugs targeting the COPD inflammatory pattern, Prof. Barnes highlighted #senolytics (like Bcl-xL inhibitors) as potential therapies to clear senescent cells. 💊 #RespiratoryMedicine #CellularSenescence