1/4 One of the most cited brain-imaging findings in this field deserves both interest and caution. I want to show what it says and where it stops.
Image: AI-generated.
@leontessar.bsky.social
@leontessar.bsky.social1/4 One of the most cited brain-imaging findings in this field deserves both interest and caution. I want to show what it says and where it stops.
Image: AI-generated.
@leontessar.bsky.socialWriting in this field tends to blend three kinds of claim: a trial with a method and a sample size, a personal story worth exactly one data point, and an interpretation of what it all means. None is worthless. They are just not the same currency.
Image: AI-generated.
@leontessar.bsky.socialA single receptor explains why some of these medicines belong together and others do not. The classic family, psilocybin and mescaline among them, acts on the serotonin 5-HT2A receptor. Ketamine works on NMDA instead. One word, different pharmacology.
@leontessar.bsky.social1/5 Three commitments hold my work together, and each one checks the other two: evidence, respect for the traditions, and honesty about risk. Lose one and you drift into dry scientism, credulity, or cheerleading.
@leontessar.bsky.socialSeason one of Tribal to Therapy is streaming in full: a trailer and 21 episodes on psychedelics, from Indigenous ceremony to clinical trials. A short map of where it goes.
@leontessar.bsky.social1/4 Two words set the tone for how I write about this subject: curious and careful. As I write in my book: “If this book does its job, you will finish it more curious and more careful at the same time.” Coming November 15.
Image: AI-generated.
@ssdpofficial.bsky.socialSSDP is a proud partner of the MAPS Psychedelic Science Conference 2027.
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