www.science.org/doi/10.1126/...
This #poxvirus has 2 copies of a human gene in it. The authors think this occurred less than 160,000 years ago.
#transposable-elements
MCV is a distant relative of smallpox, infects only humans, & causes small skin sores that resolve in a few months.

(2/3) #PKR is an antiviral protein engaged in molecular arms races with viruses. At least 4 direct PKR pathway inhibitors (E3, K3, CRV-157, CReP/GADD34 homologs), and 2 decapping enzymes that reduce the amount of the PKR activator, #dsRNA, have evolved independently in different #poxvirus lineages.

(1/3) Fresh from the press. Our new review on:
Insights into molecular mechanisms of #poxvirus evolution and host range through studies of poxvirus inhibitors of #protein_kinase_R | Journal of Virology journals.asm.org/doi/10.1128/...

Thrilled to share our latest preprint on the #evolution of gene repertoires in #poxvirus, a group of giant DNA viruses of medical importance! 🦠🧬 #smallpox #mpox

Check out the thread below for a summary of our key findings 👇