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@snpoehlm.bsky.socialOct 8, 2026, 11:17 AM

The good news: vaccination boosted neutralizing responses against many currently circulating variants, including the emerging saltation variant PJ.2.1

The less good news: neutralizing antibodies against BA.3.2 showed the weakest boost.

#BA32 #PJ21

@snpoehlm.bsky.socialOct 7, 2026, 11:24 AM

New sequences from Germany πŸ‡©πŸ‡ͺ, all collected in September. No PJ.2.1 - so far. #PJ21

@snpoehlm.bsky.socialSep 25, 2026, 1:55 PM

4 out of 50 new sequences from Syracuse, NY, USA, are PJ.2.1 #PJ21

Patients are in age groups 0-9 and 65+

@snpoehlm.bsky.socialSep 25, 2026, 1:35 PM

One new PJ.2.1 from Spain πŸ‡ͺπŸ‡Έ

The sample was collected from a one-month-old, non-hospitalized male in Vitoria-Gasteiz, northern Spain.

Among 90 newly submitted sequences - many collected in September - only one was PJ.2.1. Its spread may therefore be less robust than initially persumed. #PJ21

@snpoehlm.bsky.socialSep 22, 2026, 4:03 PM

New PJ.2.1 sequences from Spain πŸ‡ͺπŸ‡Έ

Roughly 9% of sequences from Spain collected in September are PJ.2.1

Roughly 15% of sequences from Spain submitted since September 15 are PJ.2.1 #PJ21

@snpoehlm.bsky.socialSep 22, 2026, 3:48 PM

New PJ.2.1 sequences from Spain πŸ‡ͺπŸ‡Έ

Roughly 7% of sequences from Spain collected in September are PJ.2.1

Roughly 15% of sequences from Spain submitted since September 15 are PJ.2.1 #PJ21

@snpoehlm.bsky.socialSep 17, 2026, 1:09 PM

πŸ§ͺ6 new PJ.2.1 sequences from Spain πŸ‡ͺπŸ‡Έ

Most patients were aged 55+, as expected. Two were hospitalized.

πŸ“ 4 β€” San SebastiΓ‘n
πŸ“ 1 β€” Madrid
πŸ“ 1 β€” Bilbao

PJ.2.1 is likely circulating more broadly, but only 6 of 141 samples were PJ.2.1, suggesting it is not yet dominant.

#PJ21

@snpoehlm.bsky.socialSep 16, 2026, 1:49 PM

These developments underscore the importance of maintaining at least a baseline level of genomic surveillance. #PJ21

@snpoehlm.bsky.socialSep 16, 2026, 1:47 PM

4/4 Most PJ.2.1 detections in Spain so far have been reported in older adults, in agreement with data from Canada and the US. Let's see whether this pattern continues as more cases are identified. #PJ21

@snpoehlm.bsky.socialSep 14, 2026, 8:33 PM

It is noteworthy that the initial PJ.2.1 sequences were almost exclusively obtained from patients in the above 65 years age group.

Some of the recent sequences were collected from younger individuals.

Need to monitor this development. #PJ21

@snpoehlm.bsky.socialSep 14, 2026, 3:24 PM

Two new PJ.2.1 sequences today, one from Maryland, USA πŸ‡ΊπŸ‡Έ, and one from Catalunya, Spain πŸ‡ͺπŸ‡Έ. #PJ21