Antibody Therapeutics (IF=4.8, Oxford University Press) ⚡ Review Highlight -Design and therapeutic rationale of antibody-peptide conjugates: insights from maridebart cafraglutide (AMG133) and emerging applications.
doi.org/10.1093/abt/...
#apc #amg133 #pharmacokinetics

Now available in Open Access:
Variability in Sertraline Pharmacokinetics in Routine Clinical Practice: Influence of Sex, Age, Body Weight, Smoking, and Co-Medication
#SFPT #clinical #sertraline #pharmacokinetics #ClinicalPractice #DrugMonitoring @unav.edu
onlinelibrary.wiley.com/doi/10.1111/...

Impact of #mGFR Versus #eGFR on the #Pharmacokinetics of a #Renally #Excreted Model #Drug in #Older Medical Patients: A Proof-of-Concept Trial

#VisualAbstract by @krishnadoctor1

https://www.kireports.org/article/S2468-0249(26)03252-3/fulltext

ADC development requires coordinated optimization of antigens, antibodies, linkers, and payloads. This review explores how AI and computational #Biophysics can guide rational design, patient stratification, #Pharmacokinetics, and dosing.#DrugDesign

#STTT #OpenAccess: doi.org/10.1038/s413...

Now available:
SFPT annual meeting abstracts
#pharmacology #fundamental #clinical #DrugNews #TherapeuticNews #prevention #preclinical #pharmacovigilance #pharmacoepidemiology #drug #AddictionMonitoring #opioid #chemsex #pharmacokinetics
@sfpt-fr.org
onlinelibrary.wiley.com/toc/14728206...

💊 #PBPK #modeling replaced ≥10 clinical studies for asciminib (Scemblix®) NDA—bridging doses, predicting DDIs, and informing labels. A powerful case for #model-informed #drug #development!

📌 www.mdpi.com/1999-4923/17...
#PBPK #Pharmacokinetics #DrugDevelopment #CML

💡All new articles in Bleeding Disorders: Care & Practice now include a plain language summary.

New and forthcoming in #BDCP...

🔗 https://loom.ly/uIXcNF8

#BDCP #haemophilia #pharmacokinetics #bleedingdisorders #mentalhealth #surgery #inhibitors #emicizumab #prophylaxis

#HemeSky #MedSky