@genesndiseases.bsky.socialHow is #PDL1 controlled beyond transcription?
This review explores phosphorylation, ubiquitination, glycosylation and acetylation, revealing how their crosstalk shapes immune escape and may guide #BreastCancer #immunotherapy.
@genesndiseases.bsky.socialWhy do some #LungCancer patients fail to benefit from PD-1/PD-L1 #immunotherapy?
This study identifies ANP32A as a regulator of #PDL1, showing that its loss enhances EP300/CREBBP activity and may influence treatment response.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
