In cell and rabbit steroid-induced #osteonecrosis models, a coral-inspired scaffold enabled repair: carbon #nanotubes activated PI3K-AKT to shift macrophages from inflammatory M1 to reparative M2, while nano-hydroxyapatite promoted mineralization, angiogenesis and #bone formation.👇

🦴 Osteonecrosis can progress silently before joint collapse occurs.

Reduced blood supply causes bone tissue death, most commonly affecting the femoral head.

🔗 Link: wikism.org/Osteonecrosis

#Osteonecrosis #Radiology #HipPain #SportsMedicine #Orthopedics