@oldmanclipper.bsky.socialHigher MCrp levels are found in people with osteoarthritis, correlating with more advanced stages. This protein creates an acidic microenvironment in inflamed joints, damaging cartilage and accelerating the condition. #osteoarthritis #health
@robertcfried.bsky.social
@6iccom.bsky.socialA Yale research team reports that lacosamide, an epilepsy medication, can reduce pain and rebuild cartilage when delivered via a hydrogel directly into the joint.
#science #lacosamide #osteoarthritis
@commsbio.nature.comTargeting the UCHL5/ALK5 axis reveals a deubiquitination-driven mechanism that promotes autophagy-dependent #ferroptosis in chondrocytes and accelerates #osteoarthritis progression. Read more below!
PDF available: doi.org/10.1038/s420...
@barbramon1.mas.to.ap.brid.gyStanford University scientists have discovered that blocking a specific protein that affects aging of the joints can slow down, and even reverse, damage from osteoarthritis.
#science
#medicalresearch
#Osteoarthritis
https://www.sciencedaily.com/releases/2026/10/261005011249.htm
@monalisarout1701.bsky.socialMetformin in knee osteoarthritis improves pain after 6 months.
✅ 11.4mm better pain relief with metformin vs. placebo
✅ 82% trial completion
✅ 54 received metformin; 53 placebo
#Osteoarthritis #MetforminTrial https://tnyp.me/zYGT6Yhq/s
@biomedicines.bsky.social🦴Targeting inflammation is key in osteoarthritis. This review explores how the RANK/RANKL/OPG signaling pathway drives disease progression, highlighting targeted therapies to restore joint health & reduce chronic pain.#Osteoarthritis
mdpi.com/2227-9059/12...
@vaccinologist.bsky.socialNew research suggests elevated vasopressin can activate AVPR1A in vulnerable cartilage, accelerating joint damage. The finding points to a biological link between #hypertension #highbloodpressure and #osteoarthritis beyond simple “wear and tear” www.linkedin.com/posts/drmelv...
@rheumatologyadv.bsky.socialThe presence of #osteoarthritis in multiple joints, particularly involving the knee, serves as a strong predictor for accelerated physical decline and worsening frailty in older adults.
https://www.rheumatologyadvisor.com/news/multijoint-osteoarthritis-accelerates-frailty/
@clinicaladvisor.bsky.socialEarly surveillance for #DevelopmentalDysplasia of the hip prevents long-term sequelae, including gait abnormalities and #Osteoarthritis. Read more here ⬇️ https://bit.ly/4rTFxPa
@drhowardsmith.bsky.socialA NON-SURGICAL APPROACH FOR ARTHRITIC KNEE PAIN RELIEF. A novel treatment called genicular artery embolization is emerging as a possible option. #KneeArthritis #KneePain #Osteoarthritis #KneeReplacement #GAE
@y-k-c.bsky.socialSimple treatments best for osteoarthritis?
@bionewscentral.comResearchers uncover the molecular biology behind exercise's protective effects in #aging -related #osteoarthritis, highlighting the role of #ExtracellularVesicles and their molecular cargo in producing benefits.
#Exercise #PhysicalActivity #JointHealth #CartilageHealth
@y-k-c.bsky.socialWhat are the best and worse exercises for osteoarthritis?
www.telegraph.co.uk/health-fitne...
@genesndiseases.bsky.social#Phosphorylation may hold a key to slowing #osteoarthritis.
This review shows how MAPK, PI3K/AKT and NF-κB phosphorylation regulate chondrocyte metabolism, apoptosis and inflammation, revealing new therapeutic opportunities.
#OpenAccess #GenesAndDiseases: doi.org/10.1016/j.ge...
@genesndiseases.bsky.socialWhat drives chondrocyte hypertrophy in #osteoarthritis?
This study identifies #POSTN as a regulator of #RUNX2-driven hypertrophy, with its suppression reducing cartilage damage, synovial inflammation and OA progression.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
@longevitytech.bsky.socialBelgian clinical data show Allegro’s nanotech injection Hydrocelin delivers lasting knee osteoarthritis relief from a single shot.
Link as first comment.
#longevity #geroscience #osteoarthritis #nanotech #Hydrocelin
@jmirlatestresearch.bsky.socialNew in JMIR Aging: Prediction of 2-Year Incident Clinical Knee Osteoarthritis From Extensor Mechanism Mechanical Properties in Asymptomatic Community-Dwelling Older Adults: Prospective Cohort Study #KneeOsteoarthritis #Osteoarthritis #KneeHealth #HealthyAging #SeniorHealth
@anthropology.netHuman cartilage holds a third of the cushioning sugars found in ape cartilage, even in the elbow, which apes load harder. Gene switches set before we split from Neanderthals may be why. #HumanEvolution #Osteoarthritis #Genetics www.anthropology.net/p/human-join...
@cureusmedical.bsky.socialFor decades, Europe has used low-dose radiation for painful joints. The U.S. hasn't caught on. A new Cureus review weighs LDRT's evidence and risks for osteoarthritis.
