Spreading #alphasynuclein #oligomers trigger #astrocyte/ #microglial changes and astrocyte-glutamatergic neuron system dysfunction in an age-related manner

Jaehyun LeeBae, Verena Bopp, Alicia Goreth...Karin M. Danzer #Parkinsons

link.springer.com/article/10.1...

Using human brain microvascular endothelial cells (HBMECs), scientists have demonstrated that #tau #oligomers can trigger endothelial barrier dysfunction through activation of the NLRP3 inflammasome pathway. Read more about the experimental findings on the StressMarq Blog 🍏 https://bit.ly/46K77Ev