Featured Special Issue: Critical Reviews™ in Immunology honors the late Dr. Anahid Jewett. Guest edited by Kawaljit Kaur (ImmuneLink LLC) & Subramaniam Malarkannan (Versiti; MCW): NK cell immunotherapy, engineered DCs & more. www.dl.begellhouse.com/journals/2ff... #Immunology #NKCells

🧬 Which solid tumours should NK cell therapies target? Tissue analysis, a review of 177 trials and >10,000 TCGA samples offer a framework for prioritisation @ericvivier.bsky.social

pmc.ncbi.nlm.nih.gov/articles/PMC...
#NKcells #Immunotherapy

🔬 From 9 Sep: membrane order distinguished NK-cell states with different migration and killing capacity in vitro. A useful state marker, not proof that changing membrane order improves therapy. doi.org/10.1038/s415... #NKCells

This study was led by the incredibly talented Sarah Colpitts, PhD. Huge thanks to our co-authors, collaborators, organ and blood donors, funders, and core teams.

All datasets are available:
CITE-seq: GEO GSE293758
Xenium: GEO GSE293759

#HumanImmunology #NKcells #ILC2 #ILC3 #ILCs