@jgp.orgA fluorescent non-hydrolyzable probe for the nucleotide binding sites of KATP. New study from Priscilla Rubio, Michael C. Puljung and coleagues @trinitycollege.bsky.social:
rupress.org/jgp/article/...
#Biochemistry #Biophysics #MolecularPhysiology #CellularPhysiology #IonChannels
@jgp.orgThe proximal N terminus of IRAG is required for potentiation of HCN4 channels. New study from Lucas M. Blecker, John R. Bankston and colleagues @cuanschutz.bsky.social:
rupress.org/jgp/article/...
#MolecularPhysiology #MembraneTransport #Biophysics #IonChannels
@jgp.orgHeart rate is controlled, in part, by the opening and closing of the ion channel HCN4. Blecker, Bankston and colleagues describe the functionally relevant domains of both the channel and its ER-resident potentiator, IRAG. rupress.org/jgp/article/...