@bcmfromthelabs.bsky.socialA team of scientists at Baylor College of Medicine @bcmhouston.bsky.social and the tech company @sandboxaq.bsky.social has developed a method for discovering #molecularGlues. @jinwanglab.bsky.social, H Lin et al @natcomms.nature.com #BCMPostdoc #Therapy cen.acs.org/pharmaceutic... #genengnews
@bcmfromthelabs.bsky.social#AI-based structural modeling can guide chemists early compound optimization, well before experiments reveal how a compound works. @jinwanglab.bsky.social, H Lin et al @bcmhouston.bsky.social @sandboxaq.bsky.social @natcomms.nature.com #BCMPostdoc #MolecularGlues #Therapy www.bcm.edu/news/ai-stru...
@sigtrans-sttt.bsky.socialBenzofuran-based #MolecularGlues induce aberrant head-to-head STING oligomerization, disrupting canonical signaling and suppressing interferon and inflammatory responses, revealing a therapeutic strategy for STING-driven #Autoinflammatory diseases.
