@sigtrans-sttt.bsky.social#Mitochondrial dysfunction contributes significantly to human disease pathogenesis.
This review connects #proteostasis, biogenesis, mitochondrial dynamics, and mitophagy with disease mechanisms and emerging therapeutic strategies. @ub.edu
@ijnp.bsky.socialπ’ Call for Papers: Mitochondria, Mind & Medicines
Working in #mitochondrial biology, stress research, neuroscience, psychobiology, or #metabolicpsychiatry? We invite you to contribute!
π Explore the topic
academic.oup.com/ijnp/pages/c...
@jcellsci.bsky.socialInfectious prions strain mitochondrial function
Daniel Shoup, Suzette Priola & team find that exposure of cells to prions induces changes in #mitochondrial redox state & respiration.
Highlight: journals.biologists.com/jcs/article/...
Article:
journals.biologists.com/jcs/article/...
@apspublications.bsky.socialFunction | New Article Alert! π¨ #ROS scavenging mitigates TNFΞ±-induced endoplasmic reticulum stress and #mitochondrial fragmentation in human airway smooth #muscle. Read: https://ow.ly/ePm550ZRzhJ #TNFa
@aging-us.bsky.socialβ Aging is linked to loss of #SkeletalMuscle mass and function. New #Research suggests ATF5 helps preserve #Mitochondrial quality and muscle endurance during #Aging.
@oae-evcna.bsky.socialπ¬π« From cardiac #EVs to #mitochondrial function
Region-specific human cardiac EVs exhibit distinct proteomic and lipidomic profiles and differentially regulate mitochondrial respiration and #ATP production.
π www.oaepublish.com/articles/evc...
@labogden.bsky.social @chpreusser.bsky.social
@jphysiol.bsky.socialIn this study, Evgeniia Motanova from @unipd.bsky.social and collaborators investigated preserved #mitochondrial respiration in presence of oxidative stress and reduced mitochondrial mass after 10-day bed rest in older adults π π¬
See moreποΈ
physoc.onlinelibrary.wiley.com/doi/10.1113/...
@lozanzi.bsky.social#WeekendRead! #ImmunometabolismPower #SmartTumor! Jia, Zhang &co using in vivo CRSPR show @ #ScienceImmunology that in low glucose, tumor cells steal glutamine to produce antioxidant glutathione, preventing #mitochondrial mtDNA release, #STING activation, type I #IFN & CD8 T cell antitumor activity!
@yeast-journal.bsky.socialThe new #Yeast issue of September 2026 (Volume 43, Number 5) is now out, with three research articles on various topics and two reviews on the use of yeast to study #stress biology and current methods to study #mitochondrial #metabolism and homeostasis π
@jipb.bsky.socialPMGD is the first specialized #plant #mitochondrial #genome database. This user-friendly platform with 1,829 genomes from 1,307 species across 5 major plant lineages supports plant diversity, phylogeny, and genome #evolution studies.
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantScience
@nicolasavilalab.bsky.socialImportantly, this relationship extends to #humans. Analysis of public snRNA-seq datasets showed that higher #mitochondrial gene expression in human π« #myofibers is associated with greater #macrophage abundance in the same samples