#MedNews: Unapproved #GLP-1 drugs such as retatrutide and zenagamtide are being sold on the black market, raising concerns about questionable quality and safety issues.

#MedNews: Unapproved #GLP-1 drugs such as retatrutide and zenagamtide are being sold on the black market, raising concerns about questionable quality and safety issues.
From #EASD2026 - The long-acting amylin analog petrelintide is well tolerated and can achieve clinically and statistically significant weight loss in people with #obesity compared with placebo.
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From #EASD2026 - Orforglipron, an oral non-peptide #GLP1 receptor agonist may be a feasible treatment option for patients with type 2 diabetes who are at increased cardiovascular risk.
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#MedNews: A ketogenic dietโs liver health benefits outperformed a Mediterranean diet and a low-fat plant-forward diet in a head-to-head trial of people with metabolically unhealthy obesity.
What are the real-world implications?
From #EASD2026 - Mauritius has become the first country to demonstrate a decrease in the prevalence of type 2 diabetes and intermediate hyperglycemia using the oral glucose tolerance test.
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From #EASD2026 - The first consensus recommendations for the use of #GLP1 receptor agonists during preconception, pregnancy, and the postnatal period in women with diabetes have been published.
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#MedNews - Nirsevimab is highly effective in preventing severe respiratory syncytial virus disease requiring emergency department visits, hospitalization, or intensive care unit admission.
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#MedNews - A phase 1 study has shown initial evidence that A-319, a bispecific T-cell engager, is well tolerated by patients with systemic lupus erythematosus and efficacious.
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#MedNews - Using optical coherence tomography angiography to measure vessel density may detect glaucoma progression earlier than using OCT to determine structural circumpapillary retinal nerve fiber layer thinning or visual field testing.
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#MedNews - Treatment with the novel antibodyโdrug conjugate tambotatug pelitecan significantly prolongs the survival of patients with small-cell lung cancer that has progressed after first-line therapy.
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#MedNews - People with invasive cancer have a significantly higher risk for #stroke than the general population, particularly in the initial 3 months after diagnosis and in those with pancreatic or lung cancer.
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#MedNews - An international panel of experts has proposed a framework for the use of resmetirom and semaglutide in the treatment of patients with #MASH and significant fibrosis but no cirrhosis.
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#MedNews - The risk for #ketoacidosis varies by patient characteristics among people with type 2 diabetes using #SGLT2 inhibitors and is apparent throughout treatment.
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From #ESCCongress 2026: The ACASA-TAVI and NOTION-4 trials have provided conflicting results with regard to the use of direct oral anticoagulants after #TAVI for severe aortic valve stenosis.
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#MedNews - Infants hospitalized with #pertussis have more severe outcomes with azithromycin than with clarithromycin.
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#MedNews - #Tuberculosis preventive treatment significantly reduces TB incidence and all-cause mortality in people with HIV initiating antiretroviral therapy.
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