“nHOTAIRM1 scaffolds ANXA11-dependent assemblies to drive axonal mRNA localization in human motor neurons”

How do #neurons deliver specific mRNAs to distant axons?
This work uncovered how a #lncRNA can regulate mRNA sorting in human #spMNs ⤵️
nature.com/articles/s41...

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RESEARCH PAPER: Firefox, a protein encoded by circular PVT1, is essential for MYC-driven oncogenesis
By Tiwari et al. and Anindya Bagchi
➡️ https://ow.ly/yESB50ZR92i

Also read about Honeybadger:
➡️ https://ow.ly/WsCF50ZR92k

#cancer #MYC #KRAS #lncRNA

Learn how a #lncRNA fuels #ColorectalCancer.
This study identifies AC004854.2 as a driver of c-MYC transcription through the SOX4/AC004854.2/PUF60 axis, highlighting a promising #biomarker and therapeutic target beyond WNT/β-catenin.
#GenesAndDiseases: doi.org/10.1016/j.ge...

Single #lncRNA integrates #Inflammatory and #Metabolic signals to regulate #CardiovascularHomeostasis doi.org/10.1016/j.ce... @FitzGerald__Lab #PACERR #GeneRegulation #Cyclooxygenase #TranslationalScience