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@cancers-mdpi.bsky.social Sep 16, 2026, 2:35 AM

🧩Editor's Choice
Diagnostic Performance of Line-Field Confocal Optical Coherence Tomography for #BasalCellCarcinoma: A Prospective Study
🧑‍⚕️by Carmen Orte Cano, Dilara Sanak et al. @ulbruxelles.bsky.social
5 citations so far✅
Unlock🔓 www.mdpi.com/2072-6694/18...
#LCOCT #BCC #Diagnosis

Basal cell carcinoma (BCC) is the most common form of skin cancer worldwide. Although it is rarely life-threatening, it often develops on the face, which can cause significant aesthetic concerns for patients. Its high prevalence is also associated with substantial healthcare costs. Diagnosing and subtyping BCC is key to treatment choice—topical therapies can be used for superficial BCC, while deeper forms usually require surgery—but this process typically relies on invasive biopsy. Line-field confocal optical coherence tomography (LC-OCT) is a novel non-invasive “virtual biopsy” that supports diagnosis and subtyping. In this prospective, real-life study of equivocal lesions, LC-OCT improved diagnostic confidence and showed greater accuracy than dermoscopy. The main diagnostic pitfall was confusion with sebaceous glands, while subtyping challenges included superficial trabeculated BCCs and BCC nodules extending beyond the LC-OCT’s field of view. These findings support LC-OCT as a bedside alternative to biopsies to guide treatment.

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