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@antjehellwich.bsky.social Sep 13, 2026, 2:46 PM

One Sequence, Multiple Contrasts: Toward a Simplified Knee #MRI Protocol with 3D PD TSE nDixon by Dr Romain Gillet, et al. (Service d’Imagerie Guilloz, Hôpital Central, CHRU Nancy, France).

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#RadSky #MSK #KneeMRI #MusculoskeletalRadiology

$The 3D PD TSE nDixon sequence is acquired in under six minutes and combines three complementary technologies: - isotropic 3D proton-density turbo spin-echo imaging, - Dixon fat–water separation, and - deep-learning-based image reconstruction. Unlike conventional 3D fat-suppressed TSE sequences that rely on spectral attenuated inversion recovery (SPAIR), Dixon-based reconstruction performs intrinsic fat–water separation and is considerably less sensitive to B0 field inhomogeneities. This advantage is particularly relevant in peripheral musculoskeletal imaging, where complex anatomy and off-center positioning frequently compromise conventional fat suppression. From a single acquisition, Dixon reconstruction simultaneously provides water-only images comparable to conventional PD fat-suppressed imaging together with fat-only, in-phase, and opposed-phase reconstructions. Multiple clinically useful image contrasts are therefore generated without increasing acquisition time. The availability of fat-only images is particularly valuable because they reproduce much of the information traditionally obtained from a dedicated T1-weighted sequence. Bone marrow composition, fatty replacement, marrow reconversion, incidental marrow lesions, fractures, and many bone abnormalities can therefore be evaluated without requiring an additional acquisition. Together, isotropic imaging and Dixon reconstruction create the possibility of performing a comprehensive routine knee examination using a single volumetric acquisition. Key benefits of 3D PD TSE nDixon • One acquisition, four image contrasts • Potential replacement of dedicated T1 imaging • ~ 50% shorter examination time • Isotropic multiplanar reformations • Robust Dixon fat suppression • Deep-learning reconstruction • Motion-resistant workflow • Potential extension to hand, wrist, ankle, and foot imaging WIP. Please note that 3D PD TSE nDixon is Work in Progress.$

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