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@northwell-journals.bsky.social Sep 23, 2026, 4:34 PM

Molecular Medicine - Journal
Bioengineered microtissue model of the human nigrostriatal pathway featuring centimeter-scale axon tracts and structural maturation over 6 months in vitro | #MolecularMedicine #Bioengineering #iPSC #inVitroModels #DopaminergicNeurons link.springer.com/article/10.1...

Fig. 1 Assessment and comparison of aggregated human iPSC-derived DA neuronal cultures on different coating surfaces.
Representative confocal images show comparison of neurite growth pattern of DA neurons (110,000 cells/aggregate) on ...
D- Immunocytochemistry (ICC) images validate DA neuronal markers such as βIII-tubulin (all axons, green), MAP2 (Microtubule-Associated Protein 2; soma and dendrites, gray) and TH (Tyrosine Hydroxylase; DA axons, red). E -Magnified images shown in the inset: enlarged overlay image (top) and individual channel images (bottom) highlight robust DA neuronal markers in the aggregate. F -Magnified images of peripheral neurites shown in the inset demonstrate individual
channel images of TH and βIII-tubulin.

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