#Medsky🧪 #immunosky #IDsky #publichealth understanding #mucosalimmunity & #mucosalvaccines in vaccine development
@castltrastondrs.medsky.network
@castltrastondrs.medsky.network#Medsky🧪 #immunosky #IDsky #publichealth understanding #mucosalimmunity & #mucosalvaccines in vaccine development
@castltrastondrs.medsky.network#Medsky🧪 #immunosky #oncosky #Lymphocyteactivationgene3 (LAG3) protein is a key immune inhibitory checkpoint receptor that suppresses #Tcell activation, proliferation and effector functions to maintain immune homeostasis and tolerance. In persistent pathological settings,
@braithwaiteat.bsky.socialWhich in vitro model best reflects human disease? We compared scRNA-seq profiles of >150K PBMCs across 11 stimuli, mapping them against inflammatory diseases like SLE to highlight the most clinically relevant models. Free data: doi.org/10.1186/s130... 🧪🧬🖥️ #immunosky #scRNAseq #SingleCell
@mitchmd.bsky.socialI'm pleased to announce the latest work from the Grayson Lab. Check out the disparate nature of atopy versus NRG1 in protection from lethal respiratory viral infections. This is work funded by #NIH. #Immunosky #Immunology #Medsky #virus #scRNAseq
@tuurekinnunen.bsky.socialNew research out @eurjimmunol.bsky.social: onlinelibrary.wiley.com/doi/10.1002/...
What does the immune landscape inside an inflamed joint look like in patients with juvenile idiopathic arthritis (JIA)?
We profiled synovial fluid using single-cell multiomics + flow cytometry. 👇 #immunosky 🧵 1/7
@inflames-flagship.bsky.socialExciting week ahead of us, we happy to welcome our Visiting Professor Mark Ansel to Turku, Finland! #ImmunoSky #MedSky #science
@castltrastondrs.medsky.network#Medsky🧪 #IDsky #immunosky #vaccinesmatter #publichealth XFG-adapted mRNA vaccination significantly ⏫️ neutralising activity against all tested #SARSCoV2 variants, boosting cross-reactive humoral immunity across multiple lineages.According to early immunogenicity data
www.medrxiv.org/content/10.6...
@castltrastondrs.medsky.network#Medsky🧪 #Microsky #immunosky #publichealth The autoimmune regulator (Aire) promotes #Tcell tolerance through promiscuous #geneexpression in medullary thymic epithelial cells, but growing evidence points to additional roles beyond thymic tolerance
@cellpress.bsky.social
www.cell.com/immunity/ful...
@follicular.bsky.socialMore evidence worms are good for you! 😂 Very cool study.
#Immunosky
www.nature.com/articles/s41...
@lydiabeckeriii.bsky.socialAt 12 PM today, the @britsocimm.bsky.social Manchester Immunology Group Seminar takes place in the Smith Lecture Theatre.
Dr Julie Ribot from the Gulbenkian Institute for Molecular Medicine presents her work on immune system-brain interaction: “γδ17 T cells in neuro-immune cross-talks”. #ImmunoSky
@fanofactor.bsky.social🚨 Immcantation users, don't forget to submit your 250-word abstract by October 1st!
👉 Find the template, submission instructions, and registration form here: immcantation.github.io/users-meetin...
@jennyrohn.bsky.social"P. aeruginosa subverts mucosal immunity and establishes a self-sustaining immunopathological loop, offering potential targets for #CF precision therapies."
really interesting - may have analogies in other infections too
@microbesinfect.bsky.socialA commensal-derived sugar protects against #obesity by regulating immunometabolism.
Clostridium immunis sugar lowers IL‑22 to boost visceral fat burning and counter obesity.
www.sciencedirect.com/science/arti... #microbiota #immunity #metabolism #MicroSky #ImmunoSky #MedSky
@airr-community.bsky.socialDon't forget to register for the upcoming AIRR-C Seminar Series on September 24th!
@apcmicrobiomeirel.bsky.socialA new paper in 𝐏𝐞𝐝𝐢𝐚𝐭𝐫𝐢𝐜 𝐀𝐥𝐥𝐞𝐫𝐠𝐲 𝐚𝐧𝐝 𝐈𝐦𝐦𝐮𝐧𝐨𝐥𝐨𝐠𝐲: FLORAL 2025 vs CORAL 2020. Antibiotic exposure: 13.1% vs 6.2%; peanut introduction: 44% vs 13.6%.
Paper: buff.ly/ku4RwtC
More: buff.ly/Vk9yGys
#Microbiome #Allergy #immunosky
@wiley.com @wileyhealth.bsky.social @rcsi.bsky.social
@biomedj.bsky.socialThe Mononuclear Phagocyte System: A Dispersed Organ.
Mononuclear phagocytes show broad organ roles and plasticity. This issue reviews their systemic functions beyond #immunity
www.sciencedirect.com/science/arti... #OpenAccess #immunology #ImmunoSky #MedSky
@castltrastondrs.medsky.network#Medsky🧪 #IDsky #vaccinesmatter #immunosky #publichealth The destructive nature of #COVID infection & the devastating effects of #longCOVID stem from its involvement in multiple functional signalling pathways related to host immunity. This disruption cripples our once mighty immune system.
@apcmicrobiomeirel.bsky.socialThe first longitudinal evaluation of pandemic-associated early-life exposures and childhood allergy followed the CORAL cohort to age 5.
Aeroallergen sensitisation rose from 8.9% to 24%.
buff.ly/E14lC97
buff.ly/Vk9yGys
#Allergy #immunosky
@wiley.com @wileyhealth.bsky.social @rcsi.bsky.social
@biomedj.bsky.socialDose-dependent arginine availability is associated with metabolic remodeling and immune phenotypes during development
www.sciencedirect.com/science/arti... #OpenAccess #metabolism #immunity #immunology #MedSky #ImmunoSky
@therad-lab.bsky.social🚨Spaces are filling up fast for the 2027 GRC
Immunology Fungal Infections meeting - submit your application now to avoid missing out! Full program available next week but you can see the invited speakers here:
www.grc.org/immunology-o...
#immunosky 🍄🧪