IgA Nephropathy #IgAN: Pathophysiology and Mechanistic Targets 🎯 of Potential Novel Therapies from @kdigo.org
#Nephpearls #NephSky

👉 kdigo.org/infographics/

If somebody could hurry up on this, that'd be swell.

#IgAN #nephrology #IgANephropathy

1/4 eGFR slope is now a common outcome in #IgAN trials and KDIGO has proposed a treatment target of <1 mL/min/1.73m²/year decline.
We asked: could we predict a patient’s future eGFR slope to identify risk of progression earlier?

journals.sagepub.com/doi/10.1177/...

Treatment with maximally tolerated RAASi alone does not sufficiently slow the rate of eGFR decline in high-risk patients with IgA nephropathy #IgAN, leaving patients at risk of ESKD ca. 2026 from @asnpublications.bsky.social
#Nephpearls #NephSky

👉 pubmed.ncbi.nlm.nih.gov/42584957/

Meeting Report
Outcomes from the International Society of Nephrology forum on complement therapeutics in C3 glomerulopathy and IgA nephropathy

doi.org/10.1016/j.kint.2026.08.007

#NephSky #MedSky #OpenAccess #C3G #C3Glomerulopathy #IgAN #IgANephropathy #ComplementSystem #GlomerularDisease

🎙️ NEW EPISODE
What happens when kidney function looks good, but something still isn’t right?
Brittany shares her journey with IgA nephropathy (IgAN) - from getting answers to treatment & finding her voice as a kidney patient

kidneycareuk.org/get-support/...

#IGAN #CKD #diaryofakidneywarriorpodcast

Adults with #IgAN are at greater risk of adverse kidney outcomes versus nonglomerular CKD and substantially higher risks of heart failure and death compared with no CKD ca. 2026 from @KIReports
#Nephpearls #RKDSummit #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/42027552/

Not all #IgAN therapies are created equal
#Nephpearls #RKDSummit #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/40928891/

Dipstick hemoglobinuria is associated with histologic markers of active disease in #IgAN and may provide clinically relevant information to complement current assessment of disease activity in #IgAN ca. 2026
#Nephpearls #RKDSummit #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/42628835/

Microscopic hematuria as a risk factor for #IgAN progression: considering this biomarker in selecting and monitoring patients ca. 2023
#Nephpearls #RKDSummit #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/38053974/

The Sarawak Marine Fisheries Department removed about 300kg of ghost nets from trawl-blocking reef sites in Igan waters during a three-day programme from 22 to 24 September 2026.

Full Details: sarawakdaily.com/sarawak-fish...

#Igan #Matu #SarawakNews #SarawakDaily #KuchingKing

🧬 A Phenomics commentary explores how polygenic risk scores could support earlier risk assessment and stratification in IgA nephropathy—and what is still needed before genetic risk scores enter routine clinical care.

doi.org/10.1007/s436...

#Phenomics #IgAN

Controversy:
Galactose-deficient IgA1 is the key driver of IgA nephropathy

✅Point: Suzuki & Novak
doi.org/10.1016/j.kint.2026.05.019

✅Counterpoint: Zhang et al
doi.org/10.1016/j.kint.2026.05.014

✅From the Editor: Floege
doi.org/10.1016/j.kint.2026.06.009

#NephSky #MedSky #IgAN