Among patients with #HepatocellularCarcinoma, male sex was associated with higher overall and liver-related mortality, with the association concentrated in Asian, cirrhosis, and viral-related subgroups.

Among patients with #HepatocellularCarcinoma, male sex was associated with higher overall and liver-related mortality, with the association concentrated in Asian, cirrhosis, and viral-related subgroups.
#Hypoxia makes liver cancer harder to treat.
This study shows that 3-BrPA enhances arterial #embolization, suppressing tumor growth and promoting necrosis, offering a strategy to overcome hypoxic resistance.
#currentmedicalscience: doi.org/10.1007/s115...
This study provides mechanistic insight into the anti-hepatocellular carcinoma (HCC) activity of Microhelenin C and supports the development of leukemia inhibitory factor targeted therapeutic strategies in HCC.
doi.org/10.59717/j.x...
#MicroheleninC #HepatocellularCarcinoma
Among patients with #HepatocellularCarcinoma beyond the Milan criteria who underwent #LiverTransplant, an immune checkpoint inhibitor–based pretransplant strategy was associated with better survival and lower recurrence vs therapy without immune checkpoint inhibitors. ja.ma/4hFlgbb
Could a frequently mutated gene reveal new vulnerabilities in #HepatocellularCarcinoma (HCC)?
This study identifies PTPRG as a #TumorSuppressor whose loss activates FAK/PI3K/AKT signaling, promoting HCC progression.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...
📘Read in #JEV📘 Small Extracellular Vesicle-Derived Nidogen 1 Promotes HCC Carcinogenesis via Transglutaminase 3-Mediated YAP/TAZ Signalling #extracellularvesicles #hepatocellularcarcinoma #nidogen1 #tumormicroenvironment isevjournals.onlinelibrary.wiley.com/doi/epdf/10....
A multicenter real-world study shows temperature-sensitive liquid #TACE (T-TACE) significantly improves survival and response in advanced #HepatocellularCarcinoma by promoting immune remodelling and CD8⁺ T-cell activation.
🆕New in #JEV🆕 Oxylipins-Omics Combine With Single-Molecule Analysis Identifies 13(S)-HODE Positive Extracellular Vesicles as a Diagnostic Biomarker for AFP-Negative Hepatocellular Carcinoma #extracellularvesicles #hepatocellularcarcinoma isevjournals.onlinelibrary.wiley.com/doi/epdf/10....
📢 Call for Reading | Review in #LiversMDPI
🧬 Palliative care in ESLD remains underutilized and faces barriers.
🩺 The review highlights improved symptom control and quality of life.
📖 More: www.mdpi.com/2673-4389/5/...
A team of researchers has published a comprehensive review in Cancer Biology & Medicine outlining a surgery-centered precision management framework for hepatocellular carcinoma.
#HepatocellularCarcinoma
Details: doi.org/10.20892/j.issn.2095-3941.2026.0045