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@jamanetworkopen.comOct 10, 2026, 1:00 PM

Among patients with #HepatocellularCarcinoma, male sex was associated with higher overall and liver-related mortality, with the association concentrated in Asian, cirrhosis, and viral-related subgroups.

ja.ma/4yhiQpA

Six graphs display cumulative incidence over 15 years. Top row: 'Unmatched', Bottom row: 'Matched'. In each, Female (orange) and Male (gray) curves are shown for Overall, Liver-related, and Non-liver-related mortality. Males have significantly higher Overall & Liver-related mortality (P<.001). Non-liver-related mortality shows no significant difference (P=.61, P=.65).
@currentmedscience.bsky.socialOct 8, 2026, 12:45 PM

#Hypoxia makes liver cancer harder to treat.

This study shows that 3-BrPA enhances arterial #embolization, suppressing tumor growth and promoting necrosis, offering a strategy to overcome hypoxic resistance.
#currentmedicalscience: doi.org/10.1007/s115...

#HepatocellularCarcinoma #LiverCancer

Targeting Glycolytic Enzymes with 3-Bromopyruvic Acid to Enhance the Efficacy of Interventional Embolization in Hepatocellular Carcinoma
@theinnovation.bsky.socialOct 8, 2026, 3:59 AM

This study provides mechanistic insight into the anti-hepatocellular carcinoma (HCC) activity of Microhelenin C and supports the development of leukemia inhibitory factor targeted therapeutic strategies in HCC.
doi.org/10.59717/j.x...
#MicroheleninC #HepatocellularCarcinoma

@jamaoncology.comOct 1, 2026, 3:30 PM

Among patients with #HepatocellularCarcinoma beyond the Milan criteria who underwent #LiverTransplant, an immune checkpoint inhibitor–based pretransplant strategy was associated with better survival and lower recurrence vs therapy without immune checkpoint inhibitors. ja.ma/4hFlgbb

@genesndiseases.bsky.socialSep 27, 2026, 10:30 AM

Could a frequently mutated gene reveal new vulnerabilities in #HepatocellularCarcinoma (HCC)?
This study identifies PTPRG as a #TumorSuppressor whose loss activates FAK/PI3K/AKT signaling, promoting HCC progression.
#OpenAccess in #GenesAndDiseases: doi.org/10.1016/j.ge...

@isev.orgSep 25, 2026, 12:41 PM

📘Read in #JEV📘 Small Extracellular Vesicle-Derived Nidogen 1 Promotes HCC Carcinogenesis via Transglutaminase 3-Mediated YAP/TAZ Signalling #extracellularvesicles #hepatocellularcarcinoma #nidogen1 #tumormicroenvironment isevjournals.onlinelibrary.wiley.com/doi/epdf/10....

@sigtrans-sttt.bsky.socialSep 25, 2026, 3:00 AM

A multicenter real-world study shows temperature-sensitive liquid #TACE (T-TACE) significantly improves survival and response in advanced #HepatocellularCarcinoma by promoting immune remodelling and CD8⁺ T-cell activation.

#STTT #OpenAccess: doi.org/10.1038/s413...

Temperature-sensitive liquid embolic agent transarterial chemoembolization versus drug-eluting bead transarterial chemoembolization for BCLC Stage B/C hepatocellular carcinoma: a multicenter real-world study and spatial transcriptomics profiling (CHANCE 2515)
@isev.orgSep 18, 2026, 10:33 AM

🆕New in #JEV🆕 Oxylipins-Omics Combine With Single-Molecule Analysis Identifies 13(S)-HODE Positive Extracellular Vesicles as a Diagnostic Biomarker for AFP-Negative Hepatocellular Carcinoma #extracellularvesicles #hepatocellularcarcinoma isevjournals.onlinelibrary.wiley.com/doi/epdf/10....

@liversmdpi.bsky.socialSep 11, 2026, 7:42 AM

📢 Call for Reading | Review in #LiversMDPI

🧬 Palliative care in ESLD remains underutilized and faces barriers.
🩺 The review highlights improved symptom control and quality of life.

📖 More: www.mdpi.com/2673-4389/5/...

#PalliativeCare #ESLD #Hepatology #HepatocellularCarcinoma

@transpread.bsky.socialSep 9, 2026, 8:04 AM

A team of researchers has published a comprehensive review in Cancer Biology & Medicine outlining a surgery-centered precision management framework for hepatocellular carcinoma.
#HepatocellularCarcinoma
Details: doi.org/10.20892/j.issn.2095-3941.2026.0045