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@jamacardiology.com Sep 17, 2026, 1:00 PM

🧬 Viewpoint: Current therapies for #InheritedCardiomyopathy do not prevent progressive heart failure, but #GeneticTherapy may offer future approaches that target the underlying molecular cause of disease.

Genetic mechanisms of inherited cardiomyopathies. Compares Health (normal protein), Haploinsufficiency (reduced protein, stop codon), & Dominant Negative (disrupted protein, missense). Visuals show DNA, amino acids, protein pools (normal, fewer, abnormal), plus genes & therapies (gene delivery, variant correction).

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