RNA capping emerges as a key checkpoint in T cell activation: RAM upregulation is essential for RNA cap formation, gene expression, and proliferation, linking transcriptional control to immune function. 🧬

RNA capping emerges as a key checkpoint in T cell activation: RAM upregulation is essential for RNA cap formation, gene expression, and proliferation, linking transcriptional control to immune function. 🧬
Glutamine #metabolism has diverse roles across health and disease. This review explores its links to #Cancer, #Neurodegeneration, metabolic and #cardiovasculardisorders, microbiome interactions, and emerging therapeutic strategies.
Can routine histology reveal molecular subtypes of #PancreaticCancer?
A graph-constrained model links H&E morphology with gene co-expression structure to predict basal-like and classical PDAC subtypes.
#STTT #OpenAccess: doi.org/10.1038/s413...
#GeneExpression #CancerGenomics
Unlocking Silenced Brain Genes: Is Sodium Butyrate the Ultimate Epigenetic Breakthrough?
Source: www.frontiersin.org/articles/10....
Source: www.mdpi.com/1422-0067/22...
Source: pubmed.ncbi.nlm.nih.gov/33895475/
#epigenetics #4PBA #sodiumbutyrate #BDNF #neuroscience #geneexpression #brainhealth
Half of our DNA is comprised of 'jumping genes,' thought to be parasitic codes that have outpaced our evolutionary needs, leaving them with no functional purpose. #GeneticCode #DNA #HumanGenetics #GeneExpression
#Medsky🧪 #Microsky #immunosky #publichealth The autoimmune regulator (Aire) promotes #Tcell tolerance through promiscuous #geneexpression in medullary thymic epithelial cells, but growing evidence points to additional roles beyond thymic tolerance
@cellpress.bsky.social
www.cell.com/immunity/ful...
Come join us as a #ComputationalBiology postdoc decoding #GeneExpression noise with maths & ML at @stonybrooku!
Postdoctoral positions in Quantitative Biology
Stony Brook University
See the full job description on jobRxiv: https://jobrxiv.org/job/stony-brook-university-27778-postdoctoral-position
How are mitochondrial transcription and DNA replication coordinated in Trypanosoma brucei? Torsten Ochsenreiter &co identify mtTF1, the first mitochondrial #TranscriptionFactor in Kinetoplastea required for #GeneExpression and maxicircle replication.🧪 buff.ly/ZhYVzts
Critical Reviews™ in Eukaryotic Gene Expression publishes research on genetic & epigenetic control of gene expression—cell cycle regulation, tumorigenesis, stem cell biology & regenerative medicine.
Submit: www.begellhouse.com/CRE
Critical Reviews™ in Eukaryotic Gene Expression publishes research on genetic & epigenetic control of gene expression—cell cycle regulation, tumorigenesis, stem cell biology & regenerative medicine.
Submit: www.begellhouse.com/CRE
📢 MIG Workshop: Fundamentals of biochemical modelling
🗓️ Wed, Oct 7 | ⏰ 9:30 am - 12:30 pm AEDT
📍 Kenneth Myer Building – Education Room (Ground Floor)
🎙️ Lucy Ham, Augustinas Sukys & Kaan Ocal
💰 Booking fee fully refunded
#MechanisticModelling #SingleCell #GeneExpression #StochasticModelling
How are mitochondrial transcription and DNA replication coordinated in Trypanosoma brucei? Torsten Ochsenreiter &co identify mtTF1, the first mitochondrial #TranscriptionFactor in Kinetoplastea required for #GeneExpression and maxicircle replication.🧪 buff.ly/ZhYVzts
How are mitochondrial transcription and DNA replication coordinated in Trypanosoma brucei? Torsten Ochsenreiter &co identify mtTF1, the first mitochondrial #TranscriptionFactor in Kinetoplastea required for #GeneExpression and maxicircle replication.🧪 buff.ly/ZhYVzts
📢 Call for Reading
📌Article in #LiversMDPI
🧬 Bao et al. compared liver gene expression in HBV-infected chimeric mice and HBV carriers.
🩺 IL12A was induced in mouse, but not human, livers.
Time-series transcriptomics sheds light on the rapid and dynamic response of the moss Physcomitrium patens to salt stress
www.sciencedirect.com/science/arti...
#plantscience #research #publication #geneexpression #VOC #specializedmetabolism #biosynthesis #rose @htsbiotechmoss.bsky.social
Sugar substitutes altered gene expression across generations in mice #geneexpression #gutmicrobiome #sugarsubstitutes