@haoyin.bsky.social#MetaplasticBreastCancer
#CaseReport
73 y/o♀️
24x18 mm left mass
Spindle-cell carcinoma
Poor margin
TN
Local recurrence 20 mo post-lumpectomy
🫁metastasis 32 mo
Death 40 mo
168-gene panel➡️
3 variants
PIK3R1 p.L573del
RUNX1 p.Y355fs
MYC amplif
@haoyin.bsky.social#MetaplasticBreastCancer
#CaseReport
56 y/o♀️
5.1 x 4.1 cm right breast mass
lymph nodal➖
Poorly differentiated spindle cell carcinoma
TN, AE1/AE3+, CK8/18+, EMA+, Vim+, Ki67 85%
Neoadjuvant Chemo➡️2.4x1.2x1.7 cm
2 yr disease-free post-mastectomy
