Bailles, A., Serafini, G., ..., Modes, C. D., & Tomancak, P. (2025). Anisotropic stretch biases the self-organization of actin fibers in multicellular Hydra aggregates. Proceedings of the National Academy of Sciences, 122(32), e2423437122. #EpithelialMechanics
www.pnas.org/doi/10.1073/...

Gross, B. J., Soltwedel, J. R., ..., Gomez, C., & Campàs, O. (2025). STRESS, an automated geometrical characterization of deformable particles for in vivo measurements of cell and tissue mechanical stresses. Scientific Reports, 15(1), 28599. #EpithelialMechanics
www.nature.com/articles/s41...

Rawal, S., Keshavanarayana, P., Manoj, D., Khuntia, P., Banerjee, S., ..., Spill, F., & Das, T. (2025). Edge curvature drives endoplasmic reticulum reorganization and dictates epithelial migration mode. Nature Cell Biology, 27(10), 1660–1675. #EpithelialMechanics
www.nature.com/articles/s41...

Tanida, S., Fuji, K., Lu, L., Guyomar, T., Lee, B. H., ..., Nonomura, M., & Sano, M. (2025). Predicting organoid morphology through a phase field model: Insights into cell division and lumenal pressure. PLOS Computational Biology, 21(8), e1012090. #EpithelialMechanics
doi.org/10.1371/jour...

Choi, B. J., Chen, Y.-C., & Desplan, C. (2025). Retinal calcium waves coordinate uniform tissue patterning of the Drosophila eye. Science, 390(6775), eady5541. #EpithelialMechanics
www.science.org/doi/10.1126/...

Hsiao, S., Mukenhirn, M., Werner, C., Honigmann, A., & Krieg, E. (2025). Reconfigurable Microenvironments Uncover Mechano‐Sensing Timescales and Direct Cell Polarity. Advanced Functional Materials, 35(49), e13028. #EpithelialMechanics
advanced.onlinelibrary.wiley.com/doi/10.1002/...

Bresteau, E., Suva, E. E., Revell, C., Hassan, O. A., Grata, A., Sheridan, J., Mitchell, J., ..., Jensen, O. E., & Mitchell, B. (2025). Apical size reduction by macropinocytosis alleviates tissue crowding. Nature Communications, 16(1), 5338. #EpithelialMechanics
www.nature.com/articles/s41...

Fascinating to see how patterns appear across scales and systems! 🦓🫆

Thanks @benswedlund.bsky.social for this amazing #EpithelialMechanics thread! 👇

Can maths explain the patterns of life?
Follow the story of reaction-diffusion from his 1952 paper to engineered cells that pattern themselves.

Another incredible #EpithelialMechanics thread by @benswedlund.bsky.social

Toda, S., Guan, G., Tambo, M., Morita, H., & Lim, W. A. (2026). Coupling Mechanical Regulation with Biochemical Reaction-Diffusion Circuits Yields Robust Self-Organized Pattern Formation. Synthetic Biology. #EpithelialMechanics
doi.org/10.64898/202...

Scholes, N. S., Schnoerr, D., Isalan, M., & Stumpf, M. P. H. (2019). A Comprehensive Network Atlas Reveals That Turing Patterns Are Common but Not Robust. Cell Systems, 9(3), 243–257.e4. #EpithelialMechanics
doi.org/10.1016/j.ce...

Green, J. B. A., & Sharpe, J. (2015). Positional information and reaction-diffusion: two big ideas in developmental biology combine. Development, 142(7), 1203–1211. #EpithelialMechanics
doi.org/10.1242/dev....

Glover, J. D., Sudderick, Z. R., Shih, B. B.-J., Batho-Samblas, C., Charlton, L., Krause, A. L., ..., Crichton, M. L., & Headon, D. J. (2023). The developmental basis of fingerprint pattern formation and variation. Cell, 186(5), 940–956.e20. #EpithelialMechanics
doi.org/10.1016/j.ce...

Swedlund, B., Danan, J. J., Jiang, T.-X., Ben Tahar, S., Poon, K., ..., Ehrenreich, I. M., & Morsut, L. (2026). A novel reaction-diffusion architecture for engineering self-organized patterns in mammalian cells. Synthetic Biology. #EpithelialMechanics
doi.org/10.64898/202...

Turing, A. M. (1952). The chemical basis of morphogenesis. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 237(641), 37–72. #EpithelialMechanics
doi.org/10.1098/rstb...

Sheth, R., Marcon, L., Bastida, M. F., Junco, M., Quintana, L., Dahn, R., Kmita, M., Sharpe, J., & Ros, M. A. (2012). Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism. Science, 338(6113), 1476–1480. #EpithelialMechanics
www.science.org/doi/10.1126/...

Panda, Y. A., & Fischer-Friedrich, E. (2026). Localized actin cortex perturbation generates cell-scale membrane tension gradients. Biophysics. #EpithelialMechanics
doi.org/10.64898/202...

Eddy, C. Z., Raposo, H., Manchanda, A., Wong, R., Li, F., & Sun, B. (2021). Morphodynamics facilitate cancer cells to navigate 3D extracellular matrix. Scientific Reports, 11(1), 20434. #EpithelialMechanics
www.nature.com/articles/s41...

Ishihara, K., Mukherjee, A., Gromberg, E., Brugués, J., Tanaka, E. M., & Jülicher, F. (2022). Topological morphogenesis of neuroepithelial organoids. Nature Physics. #EpithelialMechanics
www.nature.com/articles/s41...

Krueger, D., Spoelstra, W. K., Mastebroek, D. J., Kok, R. N. U., Wu, S., Nikolaev, M., Bannier-Hélaouët, M., Gjorevski, N., ..., Tans, S. J., & Clevers, H. (2025). Epithelial tension controls intestinal cell extrusion. Science, 389(6764), eadr875. #EpithelialMechanics
www.science.org/doi/10.1126/...