Fluorescence Friday 🔬💜

By Julia Orio Tejada

#FluorescenceFriday #Microscopy #Cell #Mechanobiology #Cytoskeleton

We have just launched a #callforpapers for our new #specialissue in #CYTOSKELETON on "CELLULAR RECONSTITUTION". Submission deadline is June 1, 2027. It is #FREE to publish in CYTOSKELETON. No page charges. No figure charges. No colour charges.

Coarse-grained Langevin model probes actin–microtubule networks. All strain-stiffen under shear. Spatial interactions—not linear superposition—drive synergy; cross-linker stiffness controls load sharing.
link.springer.com/article/10.1...

#Cytoskeleton #Biomechanics #BiomimeticMaterials

Have you seen this #openaccess Perspective in #Cytoskeleton? #Microtubule Destabilizing #Kinesins: A Historical Perspective and Thoughts for the Future. Check it out here: onlinelibrary.wiley.com/doi/full/10....

Netrin-1 is a key neuronal guidance cue. Find out how it travels within human neurons in this new #openaccess #research #article in #CYTOSKELETON. KIF1A-Mediated Axonal Transport of Netrin-1 in iPSC-Derived Human Forebrain Neurons. onlinelibrary.wiley.com/doi/full/10....

How reliable are measurements of #actin persistence length? Check out this new #openaccess paper in #CYTOSKELETON. Quantifying Actin Persistence Length in S. pombe and S. cerevisiae: The Impact of Data Size, Filament Length and Fitting Strategy onlinelibrary.wiley.com/doi/10.1002/...

I'm thrilled that Ondřej is presenting our findings on electric and electrochemical effects on tubulin at #cytoskeletonclub2026 – stay tuned for the full paper soon!

#Cytoskeleton #Microtubules #Actin

#Targetome
Cytoskeletal checkpoints, not molecular catalogs, may govern microglial aging: Pfn1 and Arpc4 loss trigger divergent senescence and synaptic deficits.
Details: https://www.maxapress.com/article/doi/10.48130/targetome-0026-0035
#Microglia #Cytoskeleton #BrainAging #Dementia

What happens when #Supervillin proteins are lost? Find out in this new #openaccess paper in #CYTOSKELETON. "Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin-Knockout and Supervillin-Mutant Mice". Read it here for #FREE: onlinelibrary.wiley.com/doi/10.1002/...

Pathogenic #KIF1A variants differentially disrupt axonal trafficking and impede synaptic development. New study from Jayne Aiken @aikenlab.bsky.social, Erika Holzbaur @erikaholzbaur.bsky.social and colleagues @upenn.edu:
rupress.org/jcb/article/...

#Cytoskeleton #Disease #Neuroscience #Trafficking

Attention #Kinesin fans!!! Check out this new #openaccess perspective in #CYTOSKELETON "Hyperactive KIF5A in Neurodegeneration". onlinelibrary.wiley.com/doi/10.1002/...

Happy #fluorescencefriday! Today we have the back cover of our current issue of #CYTOSKELETON. Check out the entire issue here: onlinelibrary.wiley.com/toc/19493592...

Why do kinesin-1 cargoes often move faster in cells than isolated kinesin-1 molecules do in vitro?
Explore the “#kinesin speed paradox” In this #CYTOSKELETON Perspective "The Kinesin Speed Paradox Revisited: How Can Cargoes Move Faster Than Their Motors?" onlinelibrary.wiley.com/doi/10.1002/...

The new issue of #CYTOSKELETON is now out! Check out the entire issue here: onlinelibrary.wiley.com/toc/19493592...